Industrial Purity Specifications 2,4-Dichloro-5-Nitrobenzotrifluoride for Scale-Up
- [Physicochemical Data]: Melting point 54-55°C with ≥98% GC purity validation.
- [Supply Chain]: Secure tonnage quantities with factory-direct COA verification.
- [Compliance]: HTS 2904.90.4000 classification and TSCA inventory status checks.
In the development of advanced agrochemicals and pharmaceutical intermediates, maintaining strict control over raw material specifications is paramount. NINGBO INNO PHARMCHEM CO.,LTD. operates as a premier global manufacturer dedicated to supplying critical building blocks with consistent industrial purity. For process engineers and procurement specialists, understanding the technical nuances of CAS 400-70-4 ensures seamless scale-up from laboratory synthesis to commercial production.
Technical Specifications and Quality Parameters
Reliable production depends on verified physicochemical properties. Variations in melting point or isomeric composition can significantly impact downstream reaction yields. The following table outlines the standard quality parameters expected for commercial-grade supply.
| Parameter | Specification | Analysis Method |
|---|---|---|
| Chemical Name | 2,4-Dichloro-5-nitrobenzotrifluoride | - |
| CAS Registry Number | 400-70-4 | - |
| Molecular Formula | C7H2Cl2F3NO2 | - |
| Molecular Weight | 259.99 g/mol | - |
| Purity (GC) | ≥ 98.0% | Gas Chromatography |
| Melting Point | 54.0 - 55.0 °C | DSC / Capillary |
| Appearance | Yellow Crystalline Powder | Visual |
| HTS Code | 2904.90.4000 | - |
Synthesis Routes and Impurity Profiles
For R&D teams optimizing downstream coupling reactions, knowledge of the upstream manufacturing process is vital. This intermediate is typically derived via nitration of dichlorotoluene derivatives followed by trifluoromethylation, or through chlorination of nitro-trifluoromethylbenzene precursors. The synonym 1,5-Dichloro-2-nitro-4-(trifluoromethyl)benzene is often referenced in literature regarding isomeric impurities.
High-quality batches minimize regio-isomers that could compete in nucleophilic aromatic substitution reactions. Our quality control protocols utilize HPLC and NMR validation alongside GC to ensure that the synthesis route delivers material free from excessive chlorinated byproducts. Consistency in these parameters prevents catalyst poisoning in subsequent steps, safeguarding overall process efficiency.
Procurement Stability and Regulatory Compliance
Securing a stable supply chain for halogenated nitro compounds requires a partner capable of handling hazardous materials logistics. When evaluating suppliers, procurement officers must prioritize vendors who provide comprehensive documentation. Every shipment from NINGBO INNO PHARMCHEM CO.,LTD. includes a batch-specific COA (Certificate of Analysis) and SDS to facilitate customs clearance and safety audits.
Commercial viability often hinges on the bulk price relative to purity grades. While laboratory reagents may offer 99% purity, process-scale operations often optimize cost-efficiency with ≥98% GC purity, provided the impurity profile is consistent. Buyers sourcing 2,4-Dichloro-5-nitrobenzotrifluoride for tonnage quantities should verify TSCA inventory status and REACH compliance to avoid regulatory bottlenecks in key markets.
Quality Assurance and Batch Consistency
Maintaining batch-to-batch consistency is critical for validating regulatory filings. Variations in physical form or moisture content can alter flow properties during automated dosing. Our facility employs rigorous statistical process control to ensure that industrial purity specifications remain within tight tolerances across multiple production campaigns.
To ensure this material meets your specific process requirements, we invite you to contact our technical sales team for a batch-specific COA, SDS, or bulk pricing quote.