Octylisothiazolinone Procurement Specs Sigma 46078 | Bulk OIT
Sigma Aldrich 46078 Octylisothiazolinone Procurement Specifications and Purity Profile
Procurement of 2-Octyl-2H-isothiazol-3-one requires strict adherence to purity parameters defined by analytical standards such as code 46078. This specific reference grade establishes the baseline for chromatographic purity, typically exceeding 98.0% as determined by Gas Chromatography (GC). For industrial applications, including coatings and metalworking fluids, the chemical identity must match the Molecular Formula C11H19NOS with a Molecular Weight of 213.34. Buyers must differentiate between analytical standards used for calibration and bulk industrial biocide grades used in formulation.
The physical state of high-purity Octylisothiazolinone varies from a yellow solid to a clear dark amber liquid depending on temperature and isomer stability. Key physical constants include a boiling point of 120°C and a density of 1.04 g/cm³. Solubility profiles indicate slight solubility in chloroform and ethyl acetate, with water solubility remaining below 0.1 g/100 mL at 19 ºC. These parameters are critical for quality control laboratories verifying incoming bulk shipments against reference materials.
| Parameter | Analytical Standard (Ref 46078) | Industrial Bulk Grade | Test Method |
|---|---|---|---|
| CAS Number | 26530-20-1 | 26530-20-1 | Verification |
| Purity (GC) | >98.0% | >95.0% - 99.0% | GC-MS / HPLC |
| Appearance | White or Colorless to Yellow | Light Yellow Oil / Amber Liquid | Visual / APHA |
| Water Content | <0.5% | <1.0% | Karl Fischer |
| Pack Size | 250mg - 5g | 1kg - 200kg | Commercial |
When evaluating suppliers, procurement managers should request a Certificate of Analysis (COA) that explicitly lists the retention time and mass spectrum match against the standard. Discrepancies in the refractive index, estimated at 1.5500, often indicate the presence of isomeric impurities or degradation products. Maintaining consistency with the performance benchmark set by analytical grades ensures that the active ingredient concentration in the final formulation remains effective against microbial growth.
CAS 26530-20-1 Regulatory Compliance and MSDS Documentation for Procurement
Regulatory documentation for CAS 26530-20-1 must align with global hazardous material transport and chemical inventory standards. The substance is listed on the TSCA inventory and carries the HS Code 29341000 for international trade classification. Procurement files must include a current Safety Data Sheet (SDS) that details the GHS classification, specifically symbols GHS05, GHS06, and GHS09. At NINGBO INNO PHARMCHEM CO.,LTD., all documentation is updated to reflect the latest hazard statements, including H301+H311 (Toxic if swallowed or in contact with skin) and H410 (Very toxic to aquatic life with long-lasting effects).
The material is classified under Hazard Class 8 (Corrosive) with a UN Number of UN2922 for shipping purposes. This classification dictates specific packaging group requirements (Packing Group III) and labeling protocols for logistics. Procurement teams must verify that the supplier provides precautionary statements such as P260 (Do not breathe dust/fume/gas/mist/vapours/spray) and P273 (Avoid release to the environment). Compliance with these safety statements is non-negotiable for warehouse storage and handling.
Furthermore, the chemical is identified by the FDA UNII 4LFS24GD0V and is recognized in the EPA Substance Registry System as Octhilinone. While regulatory statuses vary by region, the core safety data regarding acute toxicity (LD50 orl-rat: 550 mg/kg) remains constant. Buyers should ensure their internal EHS protocols align with the provided SDS, particularly regarding Personal Protective Equipment (PPE) requirements like faceshields, gloves, and type ABEK respirator filters.
Analytical Standard vs. Research Grade 2-Octyl-2H-isothiazol-3-one Cost Analysis
Cost structures for 2-Octyl-2H-isothiazol-3-one vary significantly based on purity certification and pack size. Analytical standards, often packaged in milligram quantities (e.g., 250mg), command a premium price per gram due to the rigorous QC testing required for chromatographic validation. In contrast, bulk preservative additive grades purchased in kilogram or drum quantities offer a substantially lower cost per unit weight. Procurement strategies should align the grade selection with the intended application to optimize expenditure.
Research grade materials, typically specified for biochemical research, may carry intermediate pricing between analytical standards and industrial bulk. For example, small pack sizes (1g to 5g) are suitable for laboratory-scale formulation testing but are economically unviable for production runs. Market data indicates that prices for gram-scale quantities can range significantly higher than bulk drum pricing. Scaling up to industrial volumes requires negotiating based on purity tolerances rather than absolute analytical perfection.
When conducting a cost analysis, factor in the stability of the material. Since the compound is incompatible with strong oxidizing agents, improper storage can lead to degradation, effectively increasing the cost per usable unit. Sourcing from a global manufacturer with robust quality assurance reduces the risk of batch failure. Long-term supply agreements often secure better pricing tiers for consistent purity levels, ensuring that the cost analysis reflects total cost of ownership rather than just initial purchase price.
Critical Storage Parameters and Hazardous Material Handling for OIT Inventory
Proper inventory management for Octylisothiazolinone (OIT) requires strict adherence to storage temperatures and compatibility checks. The recommended storage temperature is sealed in dry conditions at 2-8°C to maintain stability and prevent decomposition. Exposure to higher temperatures or moisture can alter the chemical profile, potentially reducing efficacy as a fungicide. Warehouse facilities must be equipped to handle Hazard Class 6.1A combustible acute toxic materials.
Safety protocols must address the reactivity profile of isothiazolones. The substance reacts exothermically with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, and strong oxidizers. Contact with hydrogen peroxide may form explosive material. Therefore, segregation from oxidizing agents is critical during storage. For facilities managing multiple biocides, understanding the Octylisothiazolinone Drop-In Replacement Kathon 893T compatibility profiles is essential to prevent cross-contamination or hazardous reactions in mixed inventory zones.
In the event of a spill or fire, note that heating to decomposition emits very toxic fumes of SOx and NOx. Firefighting measures should account for the potential release of these gases. The material is classified as a skin and severe eye irritant, requiring immediate washing with water in case of contact. Waste disposal must conform with EPA regulations governing storage, transportation, and treatment, particularly for generators producing waste containing this contaminant at levels ≥100 kg/mo.
Sourcing Alternatives and Bulk Pack Sizes for 2-n-Octyl-4-isothiazolin-3-one
Industrial sourcing for 2-n-Octyl-4-isothiazolin-3-one extends beyond small-scale laboratory suppliers to specialized chemical manufacturers capable of producing metric ton quantities. Bulk pack sizes typically range from 1kg drums for pilot testing to 200kg drums for full-scale production. Sourcing alternatives should be evaluated based on supply chain reliability, technical support capabilities, and consistency of the technical support provided regarding formulation integration.
For high-volume applications in paints, cooling-tower water, and leather preservation, securing a reliable supply chain is paramount. NINGBO INNO PHARMCHEM CO.,LTD. provides scalable production capacities to meet fluctuating demand without compromising on specification integrity. Buyers should verify the supplier's ability to maintain cold chain logistics if required, given the 2-8°C storage recommendation. Consistency in the supply of this equivalent active ingredient ensures stable production schedules for downstream formulators.
When selecting a bulk supplier, request samples for validation against your internal standards before committing to large volumes. Verify the availability of Octylisothiazolinone industrial biocide performance benchmark data to ensure the material meets your specific efficacy requirements. Establishing a partnership with a manufacturer who understands the nuances of isothiazolinone chemistry reduces the risk of supply disruption and quality variance.
Effective procurement of this biocide relies on balancing technical specifications with logistical safety and cost efficiency. By prioritizing verified purity data and robust safety documentation, organizations can integrate this active ingredient safely into their product lines.
To request a batch-specific COA, SDS, or secure a bulk pricing quote, please contact our technical sales team.