News Articles Tagged: Antifolate Mechanism

The Chemical Synthesis and Application of 10-Propargyl-10-deazaaminopterin

Explore the intricate chemical synthesis and critical applications of 10-Propargyl-10-deazaaminopterin (Pralatrexate CAS 146464-95-1) in cancer therapy. Learn about its role as a key intermediate.

The Science Behind Methotrexate: Mechanism of Action and Pharmacological Insights

Uncover the detailed scientific mechanisms by which Methotrexate operates as an antifolate and its broader pharmacological implications.