News Articles Tagged: Drug Resistance Mechanisms

Investigating Drug Resistance: Cisplatin and Future Cancer Therapies

Explore how understanding Cisplatin resistance informs the development of new platinum-based drugs and combination therapies.

ER Stress Response in Malaria: Artemisinin's Indirect Role

Discover how Artemisinin indirectly triggers an ER stress response in malaria parasites and its implications for drug efficacy and the development of resistance. Learn about the PK4 kinase's role.

Artemisinin and the Proteasome: A Critical Battleground Against Malaria

Investigate the critical role of the proteasome in Artemisinin's antimalarial activity and explore how targeting this cellular machinery offers new hope in combating drug-resistant malaria strains.

The Science Behind Artemisinin Resistance: A Growing Challenge

Delve into the molecular mechanisms driving Artemisinin resistance in malaria parasites and explore the scientific strategies being developed to overcome this critical global health threat.

The Science Behind YHO-13177: Enhancing Cancer Drug Efficacy Through BCRP Inhibition

Delve into the scientific details of YHO-13177, a potent BCRP inhibitor, and understand how its mechanism of action directly contributes to improving cancer drug efficacy.

Geneticin (G418 Sulfate) in Research: Applications Beyond Basic Selection

Explore the diverse applications of Geneticin (G418 Sulfate) in scientific research, extending beyond simple cell selection to critical roles in studying gene function and drug resistance.

Unlocking the Potential of Epothilone B: A Deep Dive into its Anticancer Mechanisms

Discover how Epothilone B's unique interaction with microtubules makes it a powerful weapon against cancer, including drug-resistant strains. Learn about its production and pharmaceutical significance.