The field of organic synthesis is driven by the strategic use of versatile building blocks that enable the creation of complex molecular structures. 1,2-Cyclohexanedicarboximide (CAS: 7506-66-3) stands out as a valuable intermediate, recognized for its utility in various synthetic pathways, most notably within the pharmaceutical industry. This article highlights its chemical properties, applications, and guides researchers and formulators on how to source this essential compound.

Chemical Characteristics of 1,2-Cyclohexanedicarboximide

As a chemical intermediate, 1,2-Cyclohexanedicarboximide presents with a white crystalline powder appearance. Its chemical identity is rooted in its molecular formula C8H11NO2 and a molecular weight of 153.178. Key physical properties include a density of 1.18 and a boiling point of 330.8ºC. For synthesis purposes, the purity is paramount; thus, an assay of ≥98.0% and a loss on drying of ≤1.0% are typical specifications that users should look for when they intend to buy. These specifications ensure the compound's reliability and efficacy in subsequent chemical reactions.

Applications in Organic Synthesis

The primary application driving demand for 1,2-Cyclohexanedicarboximide is its role as a key intermediate in the synthesis of Perospirone, an important antipsychotic medication. The imide structure within 1,2-Cyclohexanedicarboximide provides reactive sites that are crucial for building the complex molecular framework of Perospirone. For chemists involved in developing or manufacturing this drug, securing a consistent supply of high-quality 1,2-Cyclohexanedicarboximide from a trusted manufacturer is critical.

Beyond its pharmaceutical application, this compound serves as a versatile building block for broader organic synthesis. Its structural features can be utilized by research chemists to construct novel molecules for various applications, including agrochemicals, specialty polymers, and advanced materials. When you purchase 1,2-Cyclohexanedicarboximide, you are acquiring a fundamental unit that can be elaborated through various organic transformations.

Sourcing the Right Intermediate

For researchers and formulators, sourcing 1,2-Cyclohexanedicarboximide involves identifying reliable manufacturers and suppliers. Companies in China are often prominent suppliers, offering competitive pricing and significant production capacities. When selecting a supplier, it is essential to focus on aspects such as purity (assay ≥98.0%), consistency (low loss on drying), packaging (e.g., 25 kg drums), and delivery reliability. Engaging with chemical directories or B2B platforms can help identify potential suppliers. Obtaining Certificates of Analysis (CoA) is a standard procedure to verify product quality before making a purchase.

By understanding the chemical properties and applications of 1,2-Cyclohexanedicarboximide, and by working with reputable manufacturers, organic chemists can effectively utilize this building block to drive innovation in their synthesis projects.