In the intricate world of pharmaceutical research and development, the quality and availability of key chemical intermediates are foundational. 1-(4-Fluorophenyl)piperazine (CAS 2252-63-3) stands out as a crucial compound, widely utilized by scientists and product formulators for its versatile chemical properties. As a prominent supplier of fine chemicals, we understand the demand for high-purity intermediates that drive innovation in drug discovery.

The Chemical Profile of 1-(4-Fluorophenyl)piperazine
1-(4-Fluorophenyl)piperazine is a heterocyclic organic compound characterized by a piperazine ring substituted with a 4-fluorophenyl group. Its chemical formula is C10H13FN2, with a molecular weight of approximately 180.22 g/mol. Available typically as a clear yellowish liquid after melting, with a melting point around 30-33°C, it offers excellent solubility in common organic solvents like ethyl acetate and chloroform, though it is insoluble in water. Its purity, often exceeding 98% or 99%, is critical for its application in sensitive synthetic pathways.

Role in Pharmaceutical Synthesis
The primary utility of 1-(4-Fluorophenyl)piperazine lies in its application as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its specific structural features allow it to participate in a variety of chemical reactions, including N-alkylation, N-arylation, and other functional group transformations, enabling the construction of complex drug molecules.

• API Development: It serves as a key building block for numerous APIs across different therapeutic areas. Pharmaceutical chemists rely on its consistent quality to ensure the efficacy and safety of the final drug products.
• Drug Discovery: In the early stages of drug discovery, researchers utilize compounds like 1-(4-Fluorophenyl)piperazine to synthesize novel chemical entities for screening against various biological targets. Its availability from reliable manufacturers supports rapid library synthesis.
• Metabolite Research: Notably, 1-(4-Fluorophenyl)piperazine is recognized as a significant metabolite of Niaparazine, a sedative and hypnotic drug. This makes it valuable for pharmacokinetic studies, drug metabolism analysis, and understanding drug efficacy and side effects.

Sourcing and Quality Assurance
For companies looking to procure 1-(4-Fluorophenyl)piperazine, partnering with a reputable manufacturer and supplier is essential. We, as a dedicated supplier in China, ensure that our product meets high-quality standards, offering competitive prices and reliable delivery. Our commitment to quality assurance means that our clients can confidently integrate this intermediate into their development pipelines. Whether for small-scale R&D or larger commercial needs, we provide solutions tailored to your specific requirements. Engaging with us ensures you gain access to a dependable source for this vital pharmaceutical intermediate, supporting your mission to bring innovative medicines to market.