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1-Bromo-4-chloro-2-fluorobenzene: A Key Pharmaceutical Intermediate

In the intricate landscape of pharmaceutical manufacturing, the journey from raw materials to life-saving medications relies heavily on a class of compounds known as pharmaceutical intermediates. Among these, 1-Bromo-4-chloro-2-fluorobenzene (CAS No.: 1996-29-8) stands out as a vital component. As a colorless to light yellow liquid with a minimum purity of 97%, this compound serves as an essential building block for numerous Active Pharmaceutical Ingredients (APIs) and advanced synthesis materials.


Pharmaceutical intermediates are chemical compounds that are formed during the synthesis pathway of an API. Unlike APIs, which are the final active substances responsible for a drug's therapeutic effect, intermediates are transitional compounds. They undergo a series of precise chemical transformations, each designed to introduce specific functional groups and molecular structures, gradually building towards the complex final API. NINGBO INNO PHARMCHEM CO.,LTD. specializes in the production of high-quality intermediates like 1-Bromo-4-chloro-2-fluorobenzene, ensuring they meet the stringent demands of the global pharmaceutical industry.


The significance of intermediates in drug development is multifaceted. Firstly, they enable efficient multi-step synthesis. Breaking down the complex process of API creation into manageable intermediate stages allows for greater control over reactions, optimizing yields and minimizing unwanted side products. Secondly, intermediates are crucial for maintaining quality and consistency. Each intermediate step provides a critical checkpoint for quality control, ensuring the purity of the compound before it proceeds to the next stage. Any impurities introduced at an early stage can compromise the final API's efficacy and safety, making the quality of intermediates like 1-Bromo-4-chloro-2-fluorobenzene paramount.


Furthermore, the use of pharmaceutical intermediates contributes significantly to cost-effectiveness and scalability in drug manufacturing. By synthesizing intermediates in bulk, manufacturers can streamline production processes, reduce overall costs, and scale up production to meet global demand efficiently. This operational flexibility is vital for pharmaceutical companies looking to bring new drugs to market faster and more affordably. Intermediates also play a crucial role in pharmaceutical research and development, providing chemists with the necessary molecular foundations to explore new drug candidates and improve existing formulations.


The global pharmaceutical intermediates market is experiencing substantial growth, driven by an increasing prevalence of chronic diseases, a rising demand for generic drugs, and expanding research and development activities worldwide. This growth underscores the critical need for reliable manufacturers and suppliers who can provide high-quality, consistent, and competitively priced intermediates. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated chemical supplier, understands these market dynamics and is committed to being a dependable partner for pharmaceutical companies globally.


For those looking to buy or purchase high-grade 1-Bromo-4-chloro-2-fluorobenzene (CAS No.: 1996-29-8), selecting a reputable manufacturer and supplier is essential. NINGBO INNO PHARMCHEM CO.,LTD. offers this product, ensuring rigorous quality control measures from raw material sourcing to final product delivery. Our commitment to excellence helps our clients maintain the highest standards in their pharmaceutical production, ultimately contributing to the availability of safe and effective medications worldwide. We aim to offer competitive price points without compromising on the superior quality required for pharmaceutical applications, making us a preferred choice for your intermediate needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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