1-Chloromethyl Naphthalene (CAS 86-52-2) stands as a pivotal organic intermediate, widely recognized for its crucial role in various chemical syntheses. This versatile compound, with the molecular formula C11H9Cl and a molecular weight of 176.65 g/mol, is an indispensable building block for numerous industrial and research applications. Its unique chemical structure allows for diverse reactivity, making it a valuable asset in the production of complex organic molecules.
Physicochemically, 1-Chloromethyl Naphthalene typically appears as a white to yellow or deep brown solid, transitioning to a liquid after melting. It exhibits a melting point around 32 °C and a boiling point of approximately 291-292 °C. With a density of about 1.18 g/mL at 25 °C and a refractive index of 1.635-1.638, its stability and consistent properties are well-documented. While it is insoluble in water, it readily dissolves in common organic solvents such as benzene, ethanol, chloroform, ethyl acetate, and methanol, facilitating its use in a wide array of reaction conditions. These characteristics ensure its reliability and adaptability across different manufacturing processes.
The applications of 1-Chloromethyl Naphthalene are extensive and impactful. In the pharmaceutical industry, it serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactivity also makes it invaluable in the production of fine chemicals and daily chemical raw materials. Beyond pharmaceuticals, it is a key material in the synthesis of dye pigments and fluorescent brightening agents, contributing to the vibrant colors and enhanced luminescence of various products. Furthermore, it finds significant use in the manufacturing of synthetic resins, where its incorporation can impart desirable properties to the final polymer.
Advanced applications of this compound highlight its versatility. It has been successfully employed as an initiator in sophisticated polymerization techniques, such as atom transfer radical polymerization (ATRP) of styrene. This demonstrates its potential in creating well-defined polymers with controlled molecular weights and narrow polydispersity, crucial for high-performance materials. Moreover, 1-Chloromethyl Naphthalene plays a role in ligand-controlled regioselective nucleophilic aromatic substitution reactions, opening pathways for the precise synthesis of complex organic structures, including various diaryl ketones that are otherwise difficult to obtain. These diverse functionalities underscore its importance in both established and emerging chemical technologies.
Ensuring the highest quality and safety standards is paramount for a compound of this significance. Reputable manufacturers adhere to stringent quality control measures, typically achieving a purity of >99%. Compliance with international standards such as ISO 9001 demonstrates a commitment to excellence in production and management processes. Manufacturing facilities are often equipped with advanced analytical instrumentation and operate under strict guidelines to guarantee product consistency and integrity. A robust supply chain ensures reliable availability, catering to the global demand for this essential intermediate.
For industries and research institutions seeking a reliable source, partnering with an experienced manufacturer and supplier is crucial. Companies specializing in fine chemicals and pharmaceutical intermediates often offer comprehensive product support, including detailed analysis reports and flexible packaging options. To inquire about the price and to buy or purchase high-purity 1-Chloromethyl Naphthalene (CAS 86-52-2), it is advisable to contact established suppliers who can provide competitive pricing, timely delivery, and adhere to global quality benchmarks. Their expertise ensures that clients receive a product that meets their exact specifications for various applications.
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