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The field of pharmaceutical synthesis relies heavily on precisely engineered chemical intermediates to build complex drug molecules. Among these, 1-Formylpiperidine-4-carboxylic Acid (CAS: 84163-42-8) stands out due to its specific structural features and critical role in the production of important APIs. As a chemical building block, its utility is primarily recognized in its application as a precursor for Risperidone, a widely prescribed antipsychotic medication. Understanding its chemical properties and how to procure it efficiently is key for any pharmaceutical R&D scientist or procurement manager.
Chemical Profile of 1-Formylpiperidine-4-carboxylic Acid
This compound, appearing as a white powder, possesses the molecular formula C7H11NO3 and a molecular weight of approximately 157.17 g/mol. Its chemical structure features a piperidine ring substituted with a formyl group on the nitrogen atom and a carboxylic acid group at the 4-position. This dual functionality makes it an attractive starting material for various organic reactions, including condensations, reductions, and esterifications. The melting point of 137-138°C indicates its solid state under standard conditions.
Key Application: Intermediate for Risperidone Synthesis
The most prominent application of 1-Formylpiperidine-4-carboxylic Acid is its use as a direct intermediate in the synthesis of Risperidone (CAS: 106266-06-2). Risperidone is a second-generation antipsychotic used to treat schizophrenia, bipolar disorder, and irritability associated with autism. The structural integrity and purity of 1-Formylpiperidine-4-carboxylic Acid directly impact the yield and quality of the final Risperidone API. Pharmaceutical manufacturers looking to buy 1-Formylpiperidine-4-carboxylic Acid for this purpose seek suppliers who can guarantee consistent quality and availability.
Beyond Risperidone: Potential Research Applications
While its role in Risperidone synthesis is well-established, the versatile nature of 1-Formylpiperidine-4-carboxylic Acid also lends itself to broader applications in pharmaceutical research and development:
Procurement Guidance
When sourcing 1-Formylpiperidine-4-carboxylic Acid, consider its purity (typically >98.0%) and the reliability of the manufacturer or supplier. As a crucial intermediate, securing a stable supply chain is vital. If you are looking to purchase 1-Formylpiperidine-4-carboxylic Acid, our company, a leading Chinese supplier, offers this product with assured quality and competitive pricing. Contact us for a quotation or to discuss your specific requirements for this essential pharmaceutical intermediate.
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