1-Indanone (CAS No. 83-33-0) stands as a pivotal organic compound, recognized for its distinctive chemical structure and broad utility across various industrial sectors. This fascinating molecule, also known by synonyms such as indan-1-one, 1-Indone, or 2,3-Dihydro-1H-inden-1-one, is characterized by its five-membered carbon ring fused to a benzene ring, featuring a ketone group. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 1-Indanone, meeting the rigorous demands of global industries.

Chemically, 1-Indanone possesses the molecular formula C9H8O and a molecular weight of approximately 132.16 g/mol. In its pure form, it typically appears as a white to light yellow crystalline powder or a colorless solid, depending on specific conditions. Its physical properties are well-defined: a melting point ranging from 38-42 °C, a boiling point of around 243-245 °C at 760 mmHg, and a density of approximately 1.1 g/cm³. These consistent properties ensure its reliability in synthesis and application.

The synthesis of 1-Indanone can be achieved through several established chemical pathways. Common methods include the oxidation of indane or indene, which involves introducing an oxygen atom to form the ketone group. Another effective route is the cyclization of phenylpropionic acid, a process that forms the cyclic indanone structure. These synthetic methods highlight the compound's accessibility and its importance as a foundational building block in organic chemistry.

The applications of 1-Indanone are diverse and impactful, particularly in the pharmaceutical industry. Its most significant role is as a crucial intermediate in the synthesis of Rasagiline Mesylate, a medication primarily used for the treatment of Parkinson's disease. This application alone underscores 1-Indanone's vital contribution to modern medicine. Beyond Rasagiline Mesylate, it also serves as an intermediate in the production of other important pharmaceutical drugs, including 2-aminoindane, drinidene, pirandamine, and pyrophendane. Furthermore, 1-Indanone is known to be a substrate for the enzyme indanol dehydrogenase, indicating its relevance in biochemical processes.

Beyond pharmaceuticals, the indanone scaffold, derived from compounds like 1-Indanone, finds utility in the realm of advanced materials. Its electron-withdrawing nature, when modified, makes it a valuable component in the preparation of specialized organic compounds, such as non-fullerene acceptors (NFAs) for highly efficient organic photovoltaic devices. These derivatives can also contribute to the synthesis of chromophores exhibiting unique photo-physical properties, including large second-order optical nonlinearities, which are crucial for optoelectronic applications.

At NINGBO INNO PHARMCHEM CO.,LTD., quality assurance is paramount. We supply 1-Indanone with an assay of ≥99.0% purity, ensuring consistent performance for our customers. We offer flexible packing solutions, typically in 25 kg drums, with the capability to customize packaging according to specific customer requirements. For optimal preservation, 1-Indanone should be stored in a cool, well-ventilated place, adhering to standard chemical handling safety protocols.

As a reliable 1-Indanone manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality products and excellent service. For those seeking a competitive 1-Indanone price, our company ensures transparency and efficiency. Customers looking to buy 1-Indanone for their research or industrial needs can trust in our consistent supply and stringent quality control. We strive to make the purchase process seamless, supporting our clients' success with dependable chemical solutions.