1-Methyl-3-phenylpiperazine (CAS: 5271-27-2) stands as a significant chemical compound, widely recognized for its pivotal role in various synthetic processes. This versatile piperazine derivative, with its unique structural configuration, serves as a cornerstone in the production of advanced pharmaceutical compounds and finds applications in diverse scientific fields. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of high-quality 1-Methyl-3-phenylpiperazine, ensuring its availability for critical industrial and research needs globally.

Known scientifically as 1-Methyl-3-phenylpiperazine, and by synonyms such as N-METHYL-3-PHENYLPIPERAZINE, this compound boasts a molecular formula of C11H16N2 and a molecular weight of approximately 176.26 g/mol. Its physical characteristics are crucial for its handling and application. Typically appearing as a white to yellowish powder or an off-white solid, it exhibits a melting point generally ranging from 56 to 60 °C, with some reports indicating 58-61 °C. The boiling point is noted around 280.3 °C at 760 mmHg, or 85 °C at 0.5 mmHg, highlighting its stability under varying pressure conditions. Its density is approximately 1.0 g/cm3, and it has a flash point around 122.1 °C, important for safety considerations.

The primary and most impactful application of 1-Methyl-3-phenylpiperazine is its use as a vital intermediate in the synthesis of Mirtazapine. Mirtazapine (CAS: 61337-67-5 / 85650-52-8) is a widely prescribed antidepressant, acting as a noradrenergic and specific serotonergic antidepressant (NaSSA). The precise chemical structure of 1-Methyl-3-phenylpiperazine makes it indispensable in building the complex molecular framework of Mirtazapine, showcasing its importance in the pharmaceutical industry. Beyond this, 1-Methyl-3-phenylpiperazine has also been studied as a reference material in forensic laboratories due to its structural relation to compounds that can affect the central and autonomic nervous systems, blood pressure, and smooth muscle. These broader implications underscore its chemical significance, extending beyond a single pharmaceutical precursor role.

Ensuring the integrity and efficacy of 1-Methyl-3-phenylpiperazine requires adherence to strict storage and handling protocols. It is recommended to store this chemical in a cool, ventilated, and dark place, ideally under an inert atmosphere, due to its air-sensitive nature. Maintaining ambient temperatures (or 2-8°C for long-term preservation) is generally advised to prevent degradation and maintain its high purity, which typically exceeds 98.0%. Safety data indicates that the compound can be harmful if swallowed or in contact with skin, and it causes serious eye damage and skin irritation. Proper personal protective equipment and ventilation are essential when handling this material to mitigate potential risks.

As a leading manufacturer and supplier of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing reliable access to 1-Methyl-3-phenylpiperazine for global clients. Our production processes adhere to stringent quality control standards, ensuring that every batch meets the required specifications for purity and consistency. We understand the critical importance of dependable supply chains for pharmaceutical and research industries, and we strive to offer competitive price structures while maintaining superior product quality. For those looking to buy or purchase 1-Methyl-3-phenylpiperazine, NINGBO INNO PHARMCHEM CO.,LTD. offers flexible packaging options, including 25 kg drums, and can accommodate specific customer requirements for bulk or smaller quantities. Our expertise as a trusted supplier means you can rely on us for consistent delivery and excellent customer service, supporting your synthesis and research endeavors with this essential chemical intermediate.