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1-Phenylcyclobutanecarbonitrile (CAS 14377-68-5): Properties and Sourcing from China

1-Phenylcyclobutanecarbonitrile, identified by CAS number 14377-68-5, is a chemical compound of notable interest within the realm of organic synthesis and pharmaceutical research. As a heterocyclic intermediate, its unique molecular structure offers a versatile platform for constructing complex chemical entities. Understanding its core properties and how to effectively source it are critical for researchers and industrial chemists aiming to leverage its potential.

The physical and chemical properties of 1-Phenylcyclobutanecarbonitrile are well-documented. Typically appearing as a transparent light yellow liquid, it possesses a molecular formula of C11H11N and a molecular weight of approximately 157.21 g/mol. Its boiling point is often cited around 290.9°C at standard atmospheric pressure, or more practically, at reduced pressure (e.g., 85°C at 8 Torr). Purity levels commonly available from manufacturers range from 95% to over 98%, depending on the specific supplier and grade. These specifications are vital for procurement managers and R&D scientists when selecting a supplier, especially when considering its use in sensitive synthetic processes.

The primary applications of 1-Phenylcyclobutanecarbonitrile revolve around its role as a chemical building block. It is a crucial intermediate in the preparation of various fine chemicals and, notably, has been employed in the synthesis of specific pharmaceutical compounds, such as DGAT-1 inhibitors. This makes it a sought-after material for drug discovery and development programs. The ability to buy 1-Phenylcyclobutanecarbonitrile with guaranteed purity and timely delivery is a significant factor for research continuity.

For global procurement, China has emerged as a significant source for such specialty chemicals. Manufacturers in China, like NINGBO INNO PHARMCHEM, offer 1-Phenylcyclobutanecarbonitrile at competitive prices, often with the flexibility to accommodate bulk orders. When searching for a reliable supplier, it is important to look for those who provide detailed product specifications, safety data sheets (SDS), and can offer custom synthesis services if required. Understanding the CAS 14377-68-5 number is fundamental for accurate identification and sourcing.

In conclusion, 1-Phenylcyclobutanecarbonitrile represents a valuable asset in the chemical synthesis toolkit. By carefully considering its properties and leveraging the capabilities of experienced manufacturers and suppliers, particularly from China, researchers and businesses can secure a consistent and high-quality supply for their critical applications.

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