In the realm of advanced chemical synthesis and pharmaceutical research, understanding the properties and applications of key intermediates is fundamental. 10-Deacetylbaccatin III (CAS 32981-86-5) is one such compound, highly valued for its role as a precursor in the synthesis of critical anti-cancer drugs. As a dedicated manufacturer and supplier, we aim to provide researchers with comprehensive insights into this vital molecule.

Chemical Profile of 10-Deacetylbaccatin III

10-Deacetylbaccatin III is a complex diterpenoid, naturally extracted from sources like the yew tree. Its chemical structure, with a molecular formula of C29H36O10 and a molecular weight of approximately 544.59 g/mol, is characterized by a unique polycyclic framework. The typical appearance is a white or almost white crystalline powder, indicating a high degree of purity often essential for downstream pharmaceutical synthesis. Purity levels, typically assessed by HPLC and often exceeding 98% or 99%, are a key metric for researchers to consider when they look to purchase 10-Deacetylbaccatin III.

Key Applications in Research and Development

The primary significance of 10-Deacetylbaccatin III lies in its function as a direct precursor for the semi-synthesis of paclitaxel and docetaxel. These taxane-based chemotherapy drugs are cornerstones in the treatment of various cancers. The ability to source and utilize high-purity 10-Deacetylbaccatin III enables scientists to:

• Develop Novel Taxane Analogs: Researchers can modify the structure of 10-Deacetylbaccatin III to create new taxane derivatives with potentially improved efficacy, reduced side effects, or activity against drug-resistant cancers.
• Investigate Structure-Activity Relationships: By studying how different modifications to the 10-Deacetylbaccatin III scaffold affect biological activity, scientists can gain deeper insights into the mechanisms of action of anti-cancer agents.
• Scale-Up Pharmaceutical Production: As a reliable pharmaceutical intermediate supplier, we provide the material necessary for scaling up the synthesis of paclitaxel and docetaxel for clinical trials and commercial production.
• Serve as a Reference Standard: In analytical chemistry and quality control, pure 10-Deacetylbaccatin III can be used as a reference standard for identifying and quantifying its presence in plant extracts or synthesized products.

For those looking to order 10-Deacetylbaccatin III, it's important to partner with a manufacturer that can guarantee consistency in quality and supply. Our commitment as a Chinese supplier ensures that your research and development projects have access to this critical building block. Whether for early-stage drug discovery or for large-scale production, our high-grade 10-Deacetylbaccatin III is engineered to meet demanding R&D requirements.