2,3-Dihydrobenzofuran, identified by its CAS number 496-16-2, stands as a critical chemical compound in the realm of organic synthesis. Also known by its common synonyms such as coumaran, 2,3-dihydro-1-benzofuran, and 2,3-Dihydrobenzo[b]furan, this compound features a unique structure combining a benzene ring fused to a 2,3-dihydrofuran ring. Its distinctive molecular architecture endows it with properties that are highly sought after in various advanced chemical processes, particularly within the pharmaceutical industry.

As a colorless to light yellow transparent liquid, 2,3-Dihydrobenzofuran exhibits a consistent set of physical and chemical attributes crucial for its industrial application. It has a molecular formula of C8H8O and a molecular weight of 120.148. Key physical properties include a density of approximately 1.1 g/cm3, a boiling point of 188.2±10.0 °C at 760 mmHg, and a melting point of -21°C. Its flash point is recorded at 66.7±0.0 °C, with a vapor pressure of 0.8±0.3 mmHg at 25°C, and an index of refraction of 1.560. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our 2,3-Dihydrobenzofuran meets stringent quality specifications, with an assay typically at or above 98.0%, guaranteeing its efficacy and purity for demanding applications.

One of the most significant applications of 2,3-Dihydrobenzofuran is its indispensable role as an intermediate in the synthesis of pharmaceuticals. Most notably, it serves as a key precursor for Darifenacin hydrobromide (CAS: 133099-07-7) and Darifenacin (CAS: 133099-04-4). Darifenacin is a widely recognized pharmaceutical agent, highlighting the vital importance of 2,3-Dihydrobenzofuran in the production of essential medicines. Its reactivity and structural characteristics make it an ideal building block for creating complex organic molecules, contributing to the development of novel therapeutic compounds.

Beyond its direct involvement in Darifenacin synthesis, 2,3-Dihydrobenzofuran is a versatile scaffold in broader pharmaceutical research and development. Its heterocyclic structure can be modified to yield diverse derivatives with potential biological activities. Researchers extensively utilize this compound as an intermediate for synthesizing new chemical entities that may act as selective glucocorticoid receptor agonists, dopamine receptor ligands, anti-inflammatory agents, and in various other drug discovery pipelines. Its chemical stability and predictable reactivity enable its use in a wide range of organic transformations, making it a valuable asset for synthetic chemists pushing the boundaries of medicinal chemistry.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 2,3-Dihydrobenzofuran to meet the rigorous demands of the global chemical and pharmaceutical industries. We maintain robust quality control measures throughout the manufacturing process to ensure product consistency and purity. Our standard packaging for 2,3-Dihydrobenzofuran is 200 kg per drum, with flexible packaging options available to accommodate specific customer requirements. For optimal preservation of its properties and shelf life, the product should be stored in a cool, well-ventilated area, away from direct heat and light.

As a leading manufacturer 2,3-dihydrobenzofuran and reliable supplier 2,3-dihydrobenzofuran, NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting your research and production needs. We offer competitive 2,3-dihydrobenzofuran price and ensure efficient global distribution. If you are looking to buy 2,3-dihydrobenzofuran or purchase 2,3-dihydrobenzofuran for your projects, our team is ready to assist with your inquiries for this high-purity product. Contact us today to learn more about 2,3-dihydrobenzofuran for sale and how we can facilitate your supply chain requirements with our premium chemical solutions.