2,2-Difluoropropionic acid, also known by its synonyms such as 2,2-difluoropropanoic acid, is a crucial fluorinated organic compound identified by its CAS number 373-96-6. This chemical entity serves as a fundamental building block in various advanced synthetic processes, offering unique properties that are highly sought after in modern chemical industries.

Chemically, 2,2-Difluoropropionic acid possesses the molecular formula C3H4F2O2 and a molecular weight of 110.06. Its physical characteristics include a melting point ranging from 38 to 45 °C and a boiling point of 142 °C. The compound exhibits a density of approximately 1.3 g/cm3 and a flash point typically between 25-30°C at 5mm pressure, or 66°C. It commonly appears as a white powder to crystal form. As an organic acid, it demonstrates a pKa of around 1.34, indicating its relatively strong acidic nature. Due to its corrosive properties, appropriate safety measures are necessary during handling, including protection against skin and eye contact.

The strategic incorporation of fluorine into organic molecules has revolutionized various fields of chemistry. Fluorine's exceptional electronegativity, small atomic radius, and strong carbon-fluorine bond contribute to enhanced chemical and thermal stability, increased lipophilicity, and altered metabolic pathways in many compounds. These characteristics make fluorinated intermediates like 2,2-Difluoropropionic acid indispensable for developing molecules with improved performance and efficacy.

The applications of 2,2-Difluoropropionic acid are diverse and impactful. In pharmaceutical research and development, it is extensively used as a key intermediate for synthesizing novel drug candidates, where the fluorinated moiety can significantly improve pharmacokinetic profiles and therapeutic efficacy. For the creation of new materials, this compound contributes to the development of advanced polymers, specialty chemicals, and high-performance fluids. Furthermore, its application extends to the agricultural sector, playing a vital role in the synthesis of new pesticides and agrochemicals, optimizing their biological activity and environmental footprint. NINGBO INNO PHARMCHEM CO.,LTD. is committed to establishing a comprehensive fluorochemical products and technology platform, providing convenient one-stop services tailored to our customers' varied requirements.

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