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2,4,5-Trifluorobenzonitrile: A Key Fluorinated Building Block for Advanced Applications

2,4,5-Trifluorobenzonitrile, identified by its CAS number 98349-22-5, stands as a pivotal fluorinated chemical building block with diverse applications across multiple industries. This high-purity compound is highly valued for its unique chemical structure, featuring three fluorine atoms on a benzonitrile core, which imparts specific reactivity and stability, making it indispensable in modern chemical synthesis.

As a clear colorless to light yellow liquid, or sometimes supplied as a white powder, 2,4,5-Trifluorobenzonitrile possesses a molecular formula of C7H2F3N and a molecular weight of 157.09. Its characteristic properties include a boiling point ranging from 168-170 °C at standard pressure and a density of approximately 1.373 g/mL at 25 °C. The compound typically exhibits a purity level exceeding 98% or even 99%, ensuring its reliability for demanding synthetic pathways. It is stable at room temperature, facilitating its storage and handling. These precise specifications confirm its suitability for intricate chemical processes where consistency and high quality are paramount.

The versatility of 2,4,5-Trifluorobenzonitrile makes it a sought-after intermediate in various advanced applications.

In the pharmaceutical industry, it serves as a crucial pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates. For instance, it has been instrumental in the preparation of fluorinated analogues of potent antibiotics like platensimycin, showcasing its role in developing new therapeutic agents. Its reactive sites allow for highly regioselective substitution reactions, which are vital for constructing complex drug molecules with desired biological activities.

Beyond pharmaceuticals, 2,4,5-Trifluorobenzonitrile is a key component in the development of covalent organic frameworks (COFs). It is utilized in the synthesis of dinitrile monomers, which are then polymerized to form advanced polytriazine COFs. These materials are gaining significant attention for their exceptional properties, including high BET surface areas and remarkable gas selectivity, particularly for CO2/N2 separation. Such characteristics make COFs derived from this compound highly promising for applications in gas storage, separation technologies, and catalysis, contributing to greener industrial processes.

Furthermore, its utility extends to broader medicinal chemistry and biochemistry research. It can be used in the creation of novel linkers for solid-phase synthesis, enabling efficient and scalable production of various compounds. Researchers also explore its application in nuclear magnetic resonance (NMR) systems, specifically in generating pseudopure states for multi-qubit systems, demonstrating its relevance in cutting-edge scientific investigations.

Adherence to stringent quality control standards is paramount for a compound of this nature. Products are manufactured under strict quality management systems, often compliant with standards such as ISO 9001. This commitment ensures that every batch of 2,4,5-Trifluorobenzonitrile meets the highest industrial quality and purity requirements, providing customers with confidence in its performance and safety.

We maintain robust production capabilities, allowing for consistent supply to meet global demand. Packaging options typically include aluminum foil bags for smaller quantities like 1kg, and sturdy fiber drums for larger volumes up to 25kg, designed to preserve product integrity during transit. For high-value products, express delivery services like DDU are recommended for safety and speed. For larger consignments, air freight (CIF) or sea shipping (FOB, CFR, CIF) are available, offering flexible and cost-effective logistics solutions tailored to client needs.

For laboratories and manufacturers seeking a reliable supplier and manufacturer of 2,4,5-Trifluorobenzonitrile, we are dedicated to providing premium quality compounds. We encourage prospective clients to inquire about the current price, request detailed specifications, or explore options for bulk purchase. Whether you need a small quantity for research or a large volume for industrial scale production, our team is ready to assist with your specific requirements. To buy 2,4,5-Trifluorobenzonitrile with confidence, please reach out to our sales team for a comprehensive quotation and discuss how our high-quality chemical solutions can support your projects.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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