2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (CAS 122368-54-1) is a crucial chemical compound widely recognized for its pivotal role in the pharmaceutical industry. This versatile intermediate is indispensable in the synthesis of vital active pharmaceutical ingredients (APIs), particularly Bepotastine besilate (CAS 190786-44-8) and Bepotastine (CAS 125602-71-3). Bepotastine besilate is a well-known non-sedating H1-antagonist, valued for its potent anti-inflammatory properties, making this intermediate a cornerstone in developing advanced therapeutic solutions.
Known by several synonyms, including 2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine and (piperidin-4-yloxy)Bepotastine Intermediate, this compound possesses a distinctive molecular structure represented by the formula C17H19ClN2O. Its molecular weight stands at approximately 302.8 g/mol. Physically, 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is typically observed as a pale brown to light brown solid, though it can also present as a brown viscous liquid. Key physical and chemical properties include a density of around 1.217 g/cm³, a boiling point estimated at 421.7°C (at 760 mmHg), a melting point between 62-65°C, and a flash point of approximately 208.8°C. For optimal preservation, it should be stored in a cool, dry, and well-closed container, away from moisture and strong light or heat sources, ensuring its stability and efficacy over time.
Quality and purity are paramount for pharmaceutical intermediates, and 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine meets stringent specifications. High-quality batches typically exhibit a purity of ≥98%, with total impurities maintained at ≤0.5% and water content also at ≤0.5%. Such rigorous quality control ensures that the compound is suitable for demanding pharmaceutical applications, contributing to the safety and effectiveness of the final drug products. The standard packaging for this compound is often in 25kg cardboard drums, with provisions for customized packaging to meet specific customer requirements.
The primary application of 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine as an intermediate for Bepotastine besilate underscores its significance. Bepotastine besilate's dual action as an H1-antagonist and its anti-inflammatory effects make it crucial in treating allergic rhinitis and conjunctivitis. The reliability and consistency of this intermediate are therefore critical for pharmaceutical manufacturers globally. NINGBO INNO PHARMCHEM CO.,LTD. is a reputable manufacturer and supplier of this essential pharmaceutical intermediate, committed to delivering products that adhere to the highest industry standards. Our commitment to quality assurance and efficient production processes makes us a preferred choice for clients seeking reliable chemical solutions.
For those looking to buy 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive price options and dependable supply chain management. We invite inquiries from potential partners and customers seeking a trusted supplier for their pharmaceutical synthesis needs. Our dedicated team is ready to provide comprehensive support and facilitate your purchase with professionalism and efficiency. We ensure a seamless experience from inquiry to delivery, upholding our reputation for excellence in the global chemical market.
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