2-[5-(Bromomethyl)pyridin-2-yl]-5-methylpyridine, identified by its CAS Registry Number 117585-58-7, stands as a highly versatile and indispensable chemical intermediate in various sectors. This unique compound is a key building block due to its distinctive bipyridine structure, featuring a bromomethyl group at the 5-position and a methyl group at the 5'-position. Its molecular formula is C12H11BrN2, with a molecular weight of 263.13 g/mol, and it typically appears as an off-white solid. NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer this high-purity compound, crucial for demanding scientific and industrial applications.

The synthesis of 2-[5-(bromomethyl)pyridin-2-yl]-5-methylpyridine typically involves strategic bromination reactions. One common and effective method is the radical bromination of methyl-substituted bipyridine derivatives. This process often utilizes reagents like N-Bromosuccinimide (NBS) as the bromine source, in conjunction with a radical initiator, facilitating the selective introduction of the bromomethyl group. An alternative approach can involve stepwise functionalization from a dibrominated bipyridine precursor, allowing for precise control over the introduction of specific groups. These advanced synthetic methodologies ensure the production of a high-quality intermediate ready for complex chemical transformations.

The applications of 2-[5-(bromomethyl)pyridin-2-yl]-5-methylpyridine are diverse and significant. Primarily, it serves as an excellent ligand in coordination chemistry. Its nitrogen atoms within the bipyridine rings act as effective electron donors, forming stable chelate complexes with various transition metals. These metal complexes are invaluable in numerous catalytic processes, including important cross-coupling reactions that are fundamental to synthesizing intricate organic molecules. Furthermore, its complexes find utility in electrochemical applications, contributing to the development of advanced sensors and battery technologies due to their favorable redox properties.

Beyond catalysis, this compound holds promising potential in medicinal chemistry. Research indicates that bipyridine derivatives, particularly those with halogenated substituents, exhibit noteworthy antimicrobial activity by potentially disrupting bacterial cellular processes or inhibiting essential enzyme functions. The bipyridine framework has also been investigated for its anticancer potential, with studies suggesting its ability to induce apoptosis in cancer cells through mechanisms such as DNA damage and oxidative stress. This highlights its dual utility as both an industrial intermediate and a compound with intriguing biological properties for further pharmaceutical research.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier committed to providing high-quality 2-[5-(bromomethyl)pyridin-2-yl]-5-methylpyridine (CAS: 117585-58-7). Our rigorous quality control measures ensure that every batch meets stringent purity standards, making it ideal for precision applications in research and development. For those seeking to buy or purchase this essential chemical intermediate, we offer competitive price options and reliable global delivery. Our commitment to integrity, quality, and efficiency ensures that we meet the evolving needs of our customers worldwide, facilitating groundbreaking scientific advancements. Choose NINGBO INNO PHARMCHEM CO.,LTD. for your high-purity chemical requirements and experience unparalleled service and product excellence.