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In the intricate world of pharmaceutical research and development, the availability of precise and high-quality chemical building blocks is fundamental to innovation. 2-(5-bromopyrimidin-2-yl)acetonitrile (CAS: 831203-15-7) stands out as a vital heterocyclic intermediate, empowering scientists to synthesize novel drug candidates and advance medicinal chemistry.
The Significance of 2-(5-bromopyrimidin-2-yl)acetonitrile in Drug Discovery:
This compound's unique structure, featuring a brominated pyrimidine ring adjacent to an acetonitrile group, offers versatile reactivity. R&D scientists leverage this reactivity to introduce specific functionalities into target molecules. The pyrimidine core is a common motif in many biologically active compounds, including those with anticancer, antiviral, and anti-inflammatory properties. The bromine atom serves as an excellent leaving group for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig couplings), allowing for the facile attachment of various aryl, heteroaryl, or alkyl groups. The acetonitrile moiety can also be further transformed into carboxylic acids, amides, or amines, expanding the synthetic possibilities.
Chemical Properties and Specifications:
As a supplier of advanced chemical intermediates, we understand the importance of detailed specifications. 2-(5-bromopyrimidin-2-yl)acetonitrile (MF: C6H4BrN3, MW: 198.02) is typically supplied as a pink to orange solid. While specific physical properties like melting point might vary slightly between batches, purity is a key parameter. Scientists often look for purity levels of 97% or higher, ensuring minimal interference from impurities in their synthetic pathways. Understanding these properties is essential for successful application in complex multi-step syntheses.
How to Acquire This Crucial Intermediate:
For R&D scientists and researchers needing to buy 2-(5-bromopyrimidin-2-yl)acetonitrile, partnering with reliable manufacturers and suppliers is key. When searching for a product supplier, consider the following:
Advancing Your Research:
By securing a reliable supply of 2-(5-bromopyrimidin-2-yl)acetonitrile, pharmaceutical companies and research institutions can accelerate their discovery programs. Whether synthesizing libraries of compounds for high-throughput screening or optimizing lead compounds, having this versatile intermediate readily available is a significant advantage. We encourage R&D scientists to explore our offerings and request samples to experience the quality and reliability that our products provide, thereby facilitating your path to groundbreaking pharmaceutical innovations.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
