2,5-Dihydroxybenzaldehyde (CAS NO: 1194-98-5), also known as Gentisaldehyde, is a highly versatile and significant organic compound with a broad spectrum of applications, primarily recognized for its role as a pharmaceutical intermediate and its compelling antimicrobial properties. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of this crucial chemical, upholding stringent quality standards to meet global industry demands.

This compound presents as a distinctive yellow to khaki crystalline powder. Its molecular formula is C7H6O3, with a molecular weight of 138.12. Key physical properties include a melting point typically ranging between 97°C and 103°C and a boiling point around 276-277°C at 760 mmHg. Its density is approximately 1.4 g/cm3. The high purity of 2,5-Dihydroxybenzaldehyde, consistently exceeding 99%, ensures its reliability for demanding chemical and pharmaceutical synthesis.

2,5-Dihydroxybenzaldehyde serves as a vital building block in various synthetic pathways. It is extensively utilized as an intermediate in the synthesis of pharmaceuticals, contributing to the creation of active pharmaceutical ingredients. For instance, it plays a critical role in the synthesis of complex molecules such as hydroxy screw pyran, a crucial component in various advanced chemical structures. Beyond pharmaceuticals, it is also a key intermediate in the synthesis of dyes.

One of the most remarkable aspects of 2,5-Dihydroxybenzaldehyde is its significant biological activity. It exhibits potent antioxidant properties, particularly effective against Mycobacterium avium subsp. Paratuberculosis. Furthermore, studies have demonstrated its antibacterial activity against Staphylococcus aureus strains, showing a minimal inhibitory concentration (MIC50) of 500 mg/L. This highlights its potential in developing new antimicrobial agents, especially in contexts like preventing bovine mastitis, where antibiotic resistance is a growing concern. The compound has also been identified as a tyrosine kinase inhibitor, expanding its potential therapeutic applications.

Its versatility extends to the synthesis of novel chemical entities. 2,5-Dihydroxybenzaldehyde has been instrumental in the preparation of innovative spirochromenes, which have shown promising radical scavenging activities. It is also a key starting material in the concise syntheses of natural products like violaceoids A and C, demonstrating its importance in natural product chemistry. Additionally, it facilitates the facile preparation of various novel Schiff base complexes with metal ions such as uranyl(II), nickel(II), and zinc(II).

For industries and research institutions seeking a reliable supplier and manufacturer of 2,5-Dihydroxybenzaldehyde, NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality bulk chemical products. Our commitment to excellence ensures that every batch meets rigorous purity standards. We understand the critical importance of consistent quality for downstream applications. Clients looking to purchase this valuable chemical can expect competitive price points coupled with dependable service. We encourage prospective buyers to connect with us for inquiries regarding buy options and detailed product specifications. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting your research and industrial needs with top-tier chemical solutions.