2,5-Dimercaptoterephthalic Acid, identified by its Chemical Abstracts Service (CAS) number 25906-66-5, stands as a pivotal chemical intermediate in modern chemistry. This organic compound, often abbreviated as DMBD, is distinguished by its unique molecular structure featuring two mercapto (-SH) groups and two carboxylic acid (-COOH) groups attached to a benzene ring. This specific arrangement confers upon it exceptional reactivity and versatility, making it an indispensable building block for a myriad of synthetic applications, particularly in the realm of advanced material science. Its significance stems from its ability to form robust coordination bonds, which are crucial for constructing complex architectures.

Chemically, 2,5-Dimercaptoterephthalic Acid has a molecular formula of C8H6O4S2 and a molecular weight of 230.26 g/mol. It is also known by several synonyms, including 2,5-Disulfanylterephthalic acid and 2,5-bis(sulfanyl)terephthalic acid. Physically, this compound typically appears as a light yellow to yellow solid or powder. Key physical properties include a predicted boiling point of approximately 468.7ºC at 760mmHg and a density of around 1.648 g/cm3. For optimal storage and to maintain its high purity, it is recommended to keep 2,5-Dimercaptoterephthalic Acid at temperatures between 2-8°C, ideally under a nitrogen atmosphere, which helps prevent oxidation of the sensitive mercaptan groups. Our products consistently meet a minimum purity specification of 98%, ensuring high performance in demanding applications.

One of the most prominent applications of 2,5-Dimercaptoterephthalic Acid lies in the synthesis of Metal-Organic Frameworks (MOFs) and Covalent Organic Frameworks (COFs). These crystalline porous materials are revolutionizing various scientific fields due to their exceptionally high surface areas, tunable pore sizes, and diverse functionalities. The mercaptan groups in DMBD serve as excellent linkers, capable of coordinating with various metal ions (such as Zr(IV)), creating highly stable and functional frameworks. This precise control over structure and functionality makes MOFs derived from 2,5-Dimercaptoterephthalic Acid highly attractive for specialized applications.

A prime example of DMBD's utility in MOF synthesis is its application in environmental remediation, specifically for mercury capture and detection. Researchers have successfully synthesized mercaptan-functionalized MOFs by coordinating Zr(IV) ions with 2,5-Dimercaptoterephthalic Acid, forming Zr-DMBD MOFs. When combined with three-dimensional carbon derived from materials like kenaf stems, these nanocomposites exhibit outstanding performance in the removal and electrochemical detection of Hg(II) ions from water. The abundant mercaptan groups within the porous Zr-DMBD MOFs significantly enhance the enrichment of mercury, leading to high sensitivity and a broad linear detection range. Such materials demonstrate excellent stability and reproducibility, proving highly effective even in real wastewater samples.

Beyond environmental applications, 2,5-Dimercaptoterephthalic Acid also contributes to advanced biomedical materials. For instance, it has been integrated into UiO-66-type frameworks alongside porphyrin dopants, forming functionalized MOFs like UiO-66-(SH)2@TCPP. The presence of thiol groups from DMBD is instrumental in facilitating the subsequent encapsulation of silver nanoparticles (Ag NPs) within the framework. This is achieved through Ag(I) impregnation followed by in situ UV light reduction, resulting in a composite (UiO-66-(SH)2@TCPP@AgNPs) with remarkable antibacterial properties. These nanocomposites demonstrate enhanced reactive oxygen species (ROS) generation, effective bacterial targeting due to their nanoscale dimensions, and stable Ag NP anchoring, preventing cytotoxic leakage. This leads to high photodynamic therapy (aPDT) efficacy against both Gram-negative and Gram-positive bacteria, including MRSA, while maintaining excellent biocompatibility.

The diverse applications of 2,5-Dimercaptoterephthalic Acid underscore its significance as a versatile and high-value chemical intermediate. Its unique molecular architecture allows for tailored synthesis of advanced materials with precise functionalities, opening doors for innovation across various industries, from pharmaceuticals and fine chemicals to environmental technologies and catalysis. As research continues to uncover new avenues for MOF and COF applications, the demand for high-quality DMBD as a foundational building block is expected to grow.

For those seeking to buy or purchase 2,5-Dimercaptoterephthalic Acid (CAS 25906-66-5), it is paramount to source from a reputable manufacturer and supplier. We are committed to providing this high-purity compound, available in various packaging options including 25g, 100g, 500g, and bulk packages, to meet diverse client requirements. We understand the critical importance of product consistency and reliability in your research and industrial processes. Our dedication to quality ensures that every batch of 2,5-Dimercaptoterephthalic Acid adheres to stringent specifications, guaranteeing optimal performance. When considering the price, we offer competitive rates without compromising on quality or service. Choosing a partner who prioritizes integrity, quality, efficiency, and innovation is essential for your success. We are dedicated to providing the best products and services to meet your specific needs and foster your satisfaction.