2,6-Difluorobenzenesulfonyl Chloride (CAS No. 60230-36-6) stands as a pivotal chemical compound in the pharmaceutical industry. This highly specialized intermediate is indispensable for the synthesis of complex active pharmaceutical ingredients (APIs), particularly Dabrafenib Mesylate, a critical component in anti-cancer therapeutics. Its unique chemical structure, characterized by a sulfonyl chloride group attached to a difluorobenzene ring, grants it exceptional reactivity and selectivity, making it a valuable building block for advanced chemical synthesis.

Known by several synonyms including 2,6-Difluorobenzene-1-Sulfonyl Chloride, this compound possesses the molecular formula C6H3ClF2O2S and a molecular weight of approximately 212.6 g/mol. Typically appearing as a white to light yellow powder or clear liquid, its physical properties are well-defined. It has a boiling point of around 210 °C and a density of 1.568 g/mL at 25 °C. Given its chemical nature, 2,6-Difluorobenzenesulfonyl Chloride is moisture-sensitive and requires careful handling and storage under inert gas at cool temperatures to maintain its integrity and purity.

The primary application of 2,6-Difluorobenzenesulfonyl Chloride lies in its role as a key intermediate for Dabrafenib Mesylate. Dabrafenib Mesylate is a vital API used in the treatment of various cancers, including melanoma, by targeting specific genetic mutations. The precise and controlled synthesis of this API relies heavily on the consistent quality and high purity of intermediates like 2,6-Difluorobenzenesulfonyl Chloride. Its involvement ensures the efficacy and safety of the final pharmaceutical product, underscoring its critical importance in modern medicine.

Beyond its direct contribution to Dabrafenib Mesylate synthesis, 2,6-Difluorobenzenesulfonyl Chloride is also widely utilized in general organic synthesis, scientific research, and as a laboratory reagent for analytical purposes. Its versatility makes it a sought-after compound for developing new chemical entities and improving existing synthetic pathways. At NINGBO INNO PHARMCHEM CO.,LTD., we understand the stringent demands of the pharmaceutical sector. We are committed to producing 2,6-Difluorobenzenesulfonyl Chloride with exceptional purity, typically exceeding 98%, through rigorous quality control measures and advanced manufacturing processes.

As a dedicated manufacturer and supplier of high-quality pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. prides itself on its expertise and state-of-the-art facilities. Our production adheres to industry best practices, ensuring consistent product specifications and reliable supply. We leverage advanced synthetic methodologies, such as reactions involving difluorophenyllithium and sulfuryl chloride, to ensure efficient and scalable production. For those looking to buy 2,6-Difluorobenzenesulfonyl Chloride, our commitment to excellence makes us a preferred supplier. We offer competitive price options and support customers globally with their purchase requirements. When considering a reliable manufacturer for your pharmaceutical intermediate needs, NINGBO INNO PHARMCHEM CO.,LTD. stands ready to provide superior products and unparalleled service. Prospective clients seeking to purchase this essential intermediate are encouraged to explore our product offerings and discuss their specific requirements.