In the intricate world of organic synthesis, specific chemical compounds stand out for their versatility and importance in creating more complex molecules. 2-Amino-5-nitrobenzophenone, identified by its CAS number 1775-95-7, is one such compound. As a key pharmaceutical intermediate, its unique structural features make it an invaluable component for chemists engaged in developing new drugs and advanced materials. This article aims to shed light on its properties, applications, and the commercial aspects of procuring it from a reliable supplier.

Chemical Profile: Properties of 2-Amino-5-nitrobenzophenone

2-Amino-5-nitrobenzophenone is a crystalline solid, typically appearing as a yellow to orange powder. Its molecular formula is C13H10N2O3, and it has a molecular weight of 242.23 g/mol. The compound possesses a melting point in the range of 161-168 °C, indicating its solid state at room temperature. Its solubility characteristics are important for reaction conditions; it shows slight solubility in solvents like chloroform, DMSO, and methanol, often requiring heating for better dissolution. The presence of both an amino group and a nitro group on the benzophenone backbone offers reactive sites that are highly useful in various synthetic transformations.

Utility as a Pharmaceutical Intermediate

The pharmaceutical industry relies heavily on precisely engineered chemical intermediates to construct complex Active Pharmaceutical Ingredients (APIs). 2-Amino-5-nitrobenzophenone serves as a crucial precursor in the synthesis of several therapeutic agents. Its structure can be modified through reactions targeting the amino group, the nitro group, or the aromatic rings. For example, reduction of the nitro group can yield diamine compounds, while reactions at the amino group can introduce various substituents, leading to diverse molecular architectures. Pharmaceutical companies often buy this intermediate in bulk to ensure a continuous and cost-effective supply chain for their drug manufacturing processes.

Organic Synthesis Building Block

Beyond its pharmaceutical applications, 2-Amino-5-nitrobenzophenone is a valuable building block in broader organic synthesis. It can participate in condensation reactions, coupling reactions, and cyclization processes. Researchers use it to construct novel heterocyclic systems, dyes, or materials with specific electronic or optical properties. The ability to purchase this compound from chemical suppliers with guaranteed purity is essential for reproducible experimental results and the development of new chemical entities.

Where to Buy and Obtain Quotes

For R&D scientists and procurement specialists, finding a dependable supplier for 2-Amino-5-nitrobenzophenone is critical. Many reputable chemical manufacturers and suppliers, particularly those based in China, offer this product. When you search for a supplier, look for those who clearly list specifications such as purity (e.g., ≥97% Min.) and provide detailed safety data sheets (SDS). Obtaining quotes is straightforward; many online platforms and supplier websites allow you to request pricing for your desired quantity. Consider factors like lead time, shipping options, and customer service when making your purchasing decision. Buying high-quality 2-Amino-5-nitrobenzophenone ensures the integrity of your synthetic outcomes.

In summary, 2-Amino-5-nitrobenzophenone (CAS 1775-95-7) is a cornerstone intermediate for both pharmaceutical synthesis and general organic chemistry. Its availability from reliable manufacturers and suppliers makes it accessible for critical research and production needs.