NINGBO INNO PHARMCHEM CO.,LTD. is proud to present 2-Amino-6-chloropurine, also widely known as 6-Chloroguanine (CAS.NO: 10310-21-1). This high-quality chemical compound stands as a vital intermediate in the pharmaceutical industry, playing a crucial role in the synthesis of advanced antiviral drugs and other complex organic molecules. Our commitment to excellence ensures that this product meets the highest standards for purity and performance, making it an indispensable component for your research and development needs.

2-Amino-6-chloropurine possesses the molecular formula C5H4ClN5 and a molecular weight of 169.57200. It presents as an off-white to yellow powder, characterized by significant thermal stability with a melting point exceeding 300ºC. Its density is approximately 2.09, and it has a refractive index of 1.826. At NINGBO INNO PHARMCHEM CO.,LTD., we guarantee exceptional purity, with an assay typically registering at 99.3%, well above the standard requirement of ≥98.0%. Rigorous quality control checks confirm minimal loss on drying (≤0.5%) and residue on ignition (≤0.1%), ensuring a consistently superior product.

The primary and most significant application of 2-Amino-6-chloropurine lies in its use as a critical intermediate for the synthesis of Famciclovir. Famciclovir is a renowned antiviral medication employed in the treatment of various herpes virus infections, including herpes simplex (responsible for cold sores and genital herpes) and varicella-zoster virus (causing chickenpox and shingles). The efficient and pure synthesis of Famciclovir directly depends on the quality of its precursors, making 2-Amino-6-chloropurine an essential building block in its production process.

Beyond Famciclovir, 2-Amino-6-chloropurine serves as a versatile precursor in the synthesis of various nucleoside analogs, exhibiting potent antiviral activity against viruses such as Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6). It is also instrumental in the enzymatic synthesis of 2′-deoxyguanosine, 9-alkyl purines, and the (R)- and (S)-N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases. Furthermore, its chemical structure makes it highly useful in the broader synthesis of guanine, a fundamental component in biological systems.

As a derivative of purine, 2-Amino-6-chloropurine inherits the foundational characteristics of this important class of heterocyclic aromatic compounds. Purines, with their distinctive double-ring structure, are fundamental nitrogenous bases that form the core building blocks of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). They are not only crucial for genetic information storage and transfer but also play vital roles in cellular energy transfer (e.g., ATP, GTP), metabolic signaling, enzyme regulation, and the composition of essential coenzymes. Understanding its nature as a purine derivative highlights its biological significance and potential for diverse chemical modifications.

NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent quality standards for 2-Amino-6-chloropurine. Our comprehensive analysis includes thorough identification via HPLC and IR, precise measurement of water content, and meticulous checks for impurities such as 1,2-Dichloroethane, ash, and other single impurities, ensuring total impurities remain well below 3.0%. These rigorous tests confirm that our product consistently conforms to factory standards, providing customers with a reliable and high-performance chemical for their applications.

For packaging, 2-Amino-6-chloropurine is typically supplied in 25 kg drums, though NINGBO INNO PHARMCHEM CO.,LTD. can accommodate specific customer requirements for custom packaging. It is recommended to store this product in a cool, well-ventilated place to maintain its stability and integrity over time. As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive prices for those seeking to buy or purchase this essential intermediate. We are committed to providing top-tier products and service to support your innovative endeavors in pharmaceutical synthesis and research.