2-Bromo-4,6-diphenylpyrimidine (CAS: 56181-49-8): An Essential Chemical Intermediate

In the dynamic world of advanced chemistry, certain compounds stand out due to their versatile applications and crucial role in various industrial sectors. Among these is 2-Bromo-4,6-diphenylpyrimidine, identified by its CAS number 56181-49-8. This heterocyclic organic compound, with the molecular formula C16H11BrN2 and a molecular weight of 311.18, is a significant building block in numerous synthesis pathways. Its unique structure, featuring a pyrimidine core substituted with bromine and two phenyl groups, makes it an invaluable reagent for creating complex molecules.

The physical and chemical properties of 2-Bromo-4,6-diphenylpyrimidine are well-defined, contributing to its broad utility. It typically appears as a white powder, though it can sometimes be found in powder to light yellow crystal form. Its melting point generally ranges from 127.0 to 131.0 °C, indicating its stable crystalline structure. High purity levels, typically at or above 97%, are essential for its application in sensitive chemical reactions. For optimal preservation of its quality and integrity, this compound should be stored under an inert gas atmosphere, such as nitrogen or argon, at a temperature range of 2-8°C. This controlled storage environment prevents degradation and ensures the material maintains its efficacy for its intended uses.

The applications of 2-Bromo-4,6-diphenylpyrimidine span several critical industries. One of its most prominent uses is in the realm of OLED (Organic Light-Emitting Diode) and photoelectric materials. As a key precursor, it contributes to the synthesis of novel organic semiconductors and other advanced materials that are fundamental to developing next-generation display technologies, solar cells, and optoelectronic devices. Its inherent reactivity also positions it as a valuable intermediate in the synthesis of diverse pharmaceutical compounds. In medicinal chemistry, it can serve as a scaffold for designing new drug candidates or as a reactive site for further functionalization, leading to innovative therapeutic agents. Furthermore, its role extends to general organic synthesis as a versatile reagent for C-C coupling reactions and other transformations, allowing chemists to construct sophisticated molecular architectures.

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