2-Bromo-4-fluoro-1-nitrobenzene, identified by its CAS number 700-36-7, is a highly versatile and significant chemical compound in the realm of organic synthesis. This aromatic compound, with its unique combination of bromine, fluorine, and nitro functional groups, serves as a cornerstone for developing a wide array of more complex molecules. Its distinct chemical structure, represented by the molecular formula C6H3BrFNO2 and a molecular weight of approximately 220.00, underpins its broad utility across various industrial and research applications.

The physical and chemical properties of 2-Bromo-4-fluoro-1-nitrobenzene are well-defined, contributing to its reliability in synthetic pathways. It typically appears as a light green to yellow solid or crystalline powder. Key specifications include an assay of greater than or equal to 98.0% purity, essential for critical applications where high purity is paramount. The compound exhibits a melting point around 41-45°C, a boiling point of 224.0±20.0 °C at 760 mmHg, and a density of 1.8±0.1 g/cm3. Its flash point is recorded at 89.3±21.8 °C, with a vapor pressure of 0.1±0.4 mmHg at 25°C, and an index of refraction of 1.580. These characteristics make it a predictable and manageable reagent in chemical processes.

The applications of 2-Bromo-4-fluoro-1-nitrobenzene are diverse and impactful. Primarily, it is an indispensable intermediate for organic synthesis. Its reactivity allows for the introduction of various functional groups, making it particularly valuable in the creation of biologically active molecules. In the pharmaceutical industry, this compound is crucial for synthesizing numerous drug candidates, including those targeting bacterial infections and certain types of cancer. Its role extends to the development of agrochemicals, where it contributes to the formulation of effective pesticides and herbicides, thus supporting advancements in crop protection and agricultural productivity.

Furthermore, 2-Bromo-4-fluoro-1-nitrobenzene finds significant use in material science, aiding in the development of advanced materials such as polymers and coatings, owing to its unique electronic properties. It is also employed in analytical chemistry for the detection and quantification of nitroaromatic compounds, which is vital for environmental monitoring and pollution control. The compound's ability to undergo electrophilic substitution reactions highlights its versatility, allowing researchers to custom-design complex organic structures with precision.

For optimal stability and to maintain its high purity, 2-Bromo-4-fluoro-1-nitrobenzene should be stored in a cool and ventilated place. Standard packaging options typically include 25 kg drums, though packaging can often be customized to meet specific customer requirements. Ensuring proper storage and handling protocols is essential for preserving the integrity and efficacy of this valuable chemical intermediate.

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