2-Bromopropionyl bromide (CAS: 563-76-8) stands as a crucial chemical intermediate, widely recognized for its versatile applications across various industries, particularly in pharmaceuticals and agrochemicals. This organic compound, identified by its chemical formula C3H4Br2O and a molecular weight of 215.87100, is a colorless to pale yellow transparent liquid, exhibiting specific physical and chemical characteristics that make it invaluable in specialized synthesis processes.

Known for its distinctive properties, 2-Bromopropionyl bromide has a density of 2.061 g/mL. It possesses a melting point of 31 °C and a boiling point ranging from 48-50 °C at 10 mmHg. The flash point is noted to be above 230 °F (>110 °C), indicating its stability under certain conditions. Its refractive index is 1.518, and it is readily miscible with common organic solvents such as trichloromethane, diethyl ether, benzene, and acetone. However, it reacts adversely with water and alcohols, leading to decomposition, which necessitates careful handling and storage in cool, well-ventilated environments, protected from moisture.

The primary utility of 2-Bromopropionyl bromide lies in its role as a key intermediate. In the pharmaceutical sector, it is indispensable for the synthesis of important drugs, most notably as an intermediate for Prilocaine, a widely used local anesthetic. Its reactivity, stemming from the presence of both a carbonyl group and bromine atoms, allows it to participate effectively in nucleophilic substitution reactions, making it an efficient acylating agent in organic synthesis. Beyond pharmaceuticals, it also serves as a vital intermediate in the production of various pesticide formulations, contributing to advancements in agricultural chemistry.

Furthermore, the compound finds application in more advanced chemical syntheses. It is utilized in the preparation of cellulose macroinitiators through the direct acylation of cellulose in specific ionic liquids like 1-allyl-3-methylimidazolium chloride. It is also instrumental in creating 3-(2-bromopropionyl)-2-oxazolidone derivatives and bromoester-terminated poly(3-hexylthiophene). Its function as a macroinitiator for atom transfer radical polymerization (ATRP) of acrylates underscores its significance in polymer chemistry, enabling the development of materials with tailored properties.

Ensuring the purity and quality of 2-Bromopropionyl bromide is paramount for its effective use in sensitive applications. Typical specifications require a purity of at least 98.0%, with moisture content kept below 0.1%. Adherence to these standards guarantees optimal performance and desired outcomes in downstream reactions. The material is often supplied in 200 kg drums, with packaging options customizable to specific customer requirements.

For those seeking a reliable manufacturer or supplier of high-quality 2-Bromopropionyl bromide, securing a product that conforms to stringent factory standards is essential. When considering to buy or purchase this chemical, it is advisable to inquire about its origin and production methods. Companies with established expertise in pharmaceutical and chemical intermediates can offer competitive price points while maintaining product integrity. Partnering with a reputable chemical producer ensures a consistent supply of this critical compound for your research and industrial needs.