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2-Chloro-3-cyano-4,6-dimethylpyridine (CAS 14237-71-9): A Key Pharmaceutical Intermediate

2-Chloro-3-cyano-4,6-dimethylpyridine (CAS: 14237-71-9) stands as a pivotal chemical compound in the realm of advanced organic synthesis, particularly within the pharmaceutical industry. This versatile pyridine derivative, also widely recognized by its synonyms such as 2-chloro-4,6-dimethylnicotinonitrile, plays a crucial role as an intermediate and building block for a diverse array of complex molecules.


Chemically identified by its CAS number 14237-71-9, this compound possesses the molecular formula C8H7ClN2 and a molecular weight of 166.61 g/mol. Its physical characteristics include a melting point typically ranging from 97°C to 101°C, a predicted boiling point of approximately 305.3°C, and a density of around 1.22 g/cm3. It commonly appears as a white to almost white powder or crystal, ensuring ease of handling and storage. For optimal stability and longevity, 2-Chloro-3-cyano-4,6-dimethylpyridine should be stored under an inert atmosphere, such as nitrogen or argon, at temperatures between 2°C and 8°C.


The primary application of 2-Chloro-3-cyano-4,6-dimethylpyridine lies in its function as a key intermediate for the synthesis of various pharmaceutical active ingredients. Its unique structural features, including the chlorine, cyano, and dimethyl groups on the pyridine ring, make it an invaluable precursor for developing new drugs and fine chemicals. For instance, it is noted as a precursor or impurity in the synthesis of compounds like Opicapone, highlighting its direct relevance in the production of modern therapeutics. Beyond pharmaceuticals, it serves as an essential building block in broader organic chemistry, facilitating the creation of novel compounds for research and industrial applications.


At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying 2-Chloro-3-cyano-4,6-dimethylpyridine with exceptional purity, typically at 97% or higher. We adhere to stringent quality control measures to ensure that every batch meets the precise specifications required by our clients. While this chemical is a powerful tool for synthesis, proper handling is essential. It is classified as an irritant and can be harmful if swallowed or inhaled, causing skin irritation and serious eye damage. Users are advised to consult the safety data sheet (SDS) and follow all recommended safety precautions during handling.


NINGBO INNO PHARMCHEM CO.,LTD. prides itself on its integrity, quality, efficiency, and innovation, consistently striving to exceed customer expectations with best-in-class products and services. As a reliable manufacturer and supplier of 2-Chloro-3-cyano-4,6-dimethylpyridine, we offer competitive price options and flexible packaging solutions to meet diverse client needs. Whether you aim to buy in bulk or require smaller quantities for research, our dedicated team is ready to assist with your purchase requirements and provide comprehensive support for your projects.

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