2-Chloro-4-bromobenzaldehyde (CAS No: 158435-41-7) stands as a critical and versatile chemical intermediate, indispensable in numerous organic synthesis applications. Also known by its synonyms such as 4-Bromo-2-chlorobenzaldehyde, this compound plays a pivotal role in the creation of complex molecular structures, making it a cornerstone for advanced chemical research and industrial production.

Possessing the molecular formula C7H4BrClO and a molecular weight of 219.463 g/mol, 2-Chloro-4-bromobenzaldehyde presents as an off-white to light yellow crystalline powder. Its distinct physical and chemical properties underline its reactivity and utility in various synthesis pathways. Key specifications include a density of approximately 1.698 to 1.7 g/cm³, a boiling point around 271.3 °C, and a flash point of 117.9 °C. The compound exhibits an index of refraction of 1.623 and a melting point typically ranging from 74-76°C. These precise parameters ensure its predictable behavior in chemical reactions, crucial for high-yield and high-purity outcomes.

The primary application of 2-Chloro-4-bromobenzaldehyde lies within organic synthesis, where it serves as a fundamental building block. Its unique chemical structure, featuring both a chlorine and a bromine atom on a benzaldehyde core, allows for diverse reaction possibilities. It is particularly valued in the synthesis of heterocyclic compounds, which are integral components in pharmaceuticals, agrochemicals, and specialized materials. For instance, it has been identified as an intermediate in the preparation of P2X3 antagonists, highlighting its significance in pharmaceutical development.

Quality assurance is paramount for such a critical intermediate. This chemical is typically supplied with an assay purity of ≥98.0%, ensuring minimal impurities and optimal performance in sensitive chemical reactions. Furthermore, moisture content is rigorously controlled to be ≤0.5%, preserving the compound’s stability and reactivity. Standard packaging involves 25 kg drums, with flexible options available to meet specific customer requirements for various scales of operation.

Proper handling and storage are essential to maintain the integrity and efficacy of 2-Chloro-4-bromobenzaldehyde. It should be stored in a cool, ventilated place, preferably under an inert atmosphere, at temperatures between 2-8°C. Being air-sensitive and corrosive, appropriate safety measures must be observed, including the use of personal protective equipment. Hazard statements associated with the compound include causing skin irritation, serious eye irritation, and potential respiratory irritation.

For laboratories and industries seeking a reliable supply of this high-quality chemical intermediate, it is crucial to partner with an experienced manufacturer and supplier. A leading chemical company committed to stringent quality control ensures that every batch of 2-Chloro-4-bromobenzaldehyde meets the highest industry standards. Those looking to buy or purchase this compound should inquire about competitive price structures and comprehensive technical support. Access to a robust supply chain guarantees timely delivery and consistent product quality for all your research and development, and large-scale production needs.