In the expansive realm of pharmaceutical chemistry, certain compounds stand out for their pivotal roles in the synthesis and quality control of essential medications. Among these is 2-Chloro-6,7-dimethoxyquinazolin-4-amine, identified by its Chemical Abstracts Service (CAS) number 23680-84-4. This versatile compound, also known by synonyms such as 2-Chloro-4-amino-6,7-dimethoxyquinazoline, is a cornerstone in the production of vital active pharmaceutical ingredients (APIs) and an indispensable reference standard for impurity profiling.

The chemical profile of 2-Chloro-6,7-dimethoxyquinazolin-4-amine reveals its robust nature. With a molecular formula of C10H10ClN3O2 and a molecular weight of 239.66, it typically presents as a white or off-white crystalline powder. Its physical properties are well-defined: a melting point ranging from 262-268 °C (with decomposition), a boiling point of 374 °C at 760 mmHg, and a density of approximately 1.391 g/cm³. These characteristics ensure its stability and predictable behavior in various chemical processes.

A primary application of 2-Chloro-6,7-dimethoxyquinazolin-4-amine lies in its function as an intermediate for Prazosin hydrochloride (CAS: 19237-84-4). Prazosin hydrochloride is a widely recognized alpha-adrenergic blocker, primarily prescribed for the treatment of hypertension (high blood pressure) and symptomatic benign prostatic hyperplasia. The precise and high-quality synthesis of this intermediate is paramount to ensuring the efficacy and safety of the final Prazosin product.

Beyond its role in synthesis, this compound is also critically important as an impurity reference standard. It is recognized as Impurity A for Prazosin Hydrochloride, Impurity B for Alfuzosin Hydrochloride, Impurity A for Terazosin Hydrochloride Dihydrate, and Impurity F or Related Compound C for Doxazosin Mesilate. These applications highlight its significance in pharmaceutical quality control, enabling manufacturers to accurately identify, quantify, and control potential impurities in their final drug products, thereby ensuring compliance with stringent regulatory standards worldwide.

At NINGBO INNO PHARMCHEM CO.,LTD., our commitment to excellence is reflected in the superior quality of 2-Chloro-6,7-dimethoxyquinazolin-4-amine we provide. Our product adheres to rigorous specifications, boasting a purity of ≥99.5% (HPLC) and minimal impurities, including less than 0.5% total impurities. Each batch undergoes meticulous analysis, ensuring consistency, reliability, and conformance to the highest industry standards. We understand that in pharmaceutical manufacturing, the integrity of every intermediate is critical to the success and safety of the final therapeutic agent.

For pharmaceutical manufacturers, research institutions, and chemical distributors seeking to buy or purchase 2-Chloro-6,7-dimethoxyquinazolin-4-amine, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable manufacturer and supplier. We offer this high-grade chemical with competitive price structures, supported by efficient logistics and dedicated customer service. Our global supply chain ensures that clients can procure this essential compound securely and on schedule, meeting their production and research demands without compromise. We package the product in 25kg cardboard drums or according to specific customer requirements, ensuring its integrity during storage and transport. It is recommended to store it in a cool, dry, and well-closed container, away from moisture and strong light or heat.

The multifaceted importance of 2-Chloro-6,7-dimethoxyquinazolin-4-amine, both as a synthetic intermediate and a critical impurity standard, underscores its value in modern pharmacology. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to fostering advancements in the pharmaceutical sector by providing superior chemical solutions, enabling our partners to innovate and deliver life-changing medications.