In the vast landscape of chemical intermediates, certain compounds stand out due to their versatility and indispensable role in synthesis. 2-Chloroanisole (CAS 766-51-8) is one such molecule, serving as a crucial building block in various industrial applications, particularly in organic synthesis. This article provides a detailed look at its properties, common uses, and essential advice for procurement professionals looking to purchase this chemical.

Key Properties of 2-Chloroanisole

2-Chloroanisole, with the CAS number 766-51-8, is characterized by its physical and chemical attributes. Typically, it appears as a colorless to light yellow liquid. Its molecular formula is C7H7ClO, and it has a molecular weight of approximately 142.58 g/mol. Essential physical properties include:

• Melting Point: -27°C
• Boiling Point: 195-196°C (at standard pressure)
• Density: Approximately 1.123 g/mL at 25°C
• Flash Point: 169°F (76°C)
• Refractive Index: n20/D 1.545

These properties dictate its handling, storage, and application parameters. The high boiling point and relatively high flash point make it manageable in industrial settings, provided appropriate safety precautions are taken. Its solubility characteristics also favor its use in organic solvents, which is common in synthetic chemistry.

Primary Uses and Applications

The primary utility of 2-Chloroanisole lies in its function as an intermediate in organic synthesis. It serves as a valuable starting material for the preparation of a wide array of more complex chemical compounds. Key applications include:

• Pharmaceutical Intermediates: It is instrumental in synthesizing various active pharmaceutical ingredients (APIs) and their precursors, contributing to the development of new drugs and treatments.
• Agrochemicals: 2-Chloroanisole is used in the production of certain pesticides, herbicides, and other crop protection agents, aiding in agricultural productivity and pest management.
• Fine Chemicals: It acts as a building block for various fine chemicals used in specialized industrial applications, including dyes, pigments, and advanced materials.
• Research and Development: Its well-defined reactivity makes it a staple reagent in research laboratories for exploring new synthetic routes and developing novel chemical entities.

Sourcing 2-Chloroanisole: A Guide for Buyers

When seeking to purchase 2-Chloroanisole, especially in bulk quantities, buyers often turn to manufacturers and suppliers in China due to competitive pricing and production capacity. Here are key considerations:

• Purity and Specifications: Always verify the purity level (assay), typically ≥98.0%, and moisture content (≤0.2%) to ensure it meets your specific application needs.
• Manufacturer Reliability: Choose suppliers with a strong reputation for quality control and consistent production. Requesting Certificates of Analysis (CoA) for each batch is standard practice.
• Pricing and Quotations: Obtain multiple quotes to compare prices for the required quantity. Direct manufacturers often offer more favorable pricing.
• Lead Times and Packaging: Discuss production lead times and suitable packaging options (e.g., 200 kg drums) to ensure seamless integration into your supply chain.

By understanding the properties and applications of 2-Chloroanisole, and by diligently sourcing from reputable manufacturers, industries can reliably leverage this versatile intermediate for their ongoing success.