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2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol, identified by its CAS number 121660-11-5, stands as a pivotal chemical compound within the pharmaceutical industry. This highly specialized organic intermediate plays a critical role in the synthesis of advanced medicinal products, particularly in the production of HMG-CoA reductase inhibitors. Its unique molecular structure and specific reactivity make it indispensable for achieving the desired efficacy and safety profiles of downstream pharmaceutical active ingredients. As a prominent manufacturer of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. recognizes the immense value and demand for this compound in global drug development.
The chemical profile of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol is defined by its molecular formula, C19H16FNO, and a molecular weight of 293.33. This compound typically presents as a white solid, indicating its stable crystalline structure. Key physical properties include a melting point ranging from 134 to 136°C, a boiling point of approximately 474.7±45.0°C at 760 mmHg, and a flash point of 240.9±28.7°C. Its density is recorded at 1.286. In terms of solubility, it is slightly soluble in both chloroform and methanol, which informs its handling and processing in chemical synthesis. Optimal storage conditions recommend temperatures between 2-8°C to maintain its integrity and purity over time.
The most significant application of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol lies in its function as a crucial intermediate for Pitavastatin. Pitavastatin is a widely prescribed statin drug, renowned for its effectiveness in lowering cholesterol levels and preventing cardiovascular diseases by inhibiting HMG-CoA reductase. The precise molecular architecture of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol is essential for building the core structure of Pitavastatin, ensuring its pharmacological activity. Its consistent quality is therefore paramount for the efficient and safe production of this vital medication, directly impacting public health outcomes globally.
At NINGBO INNO PHARMCHEM CO.,LTD., adherence to stringent quality control measures ensures that 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol consistently meets high purity standards, typically at 97% or higher. Our robust production processes are designed to deliver a product free from contaminants, guaranteeing its suitability for sensitive pharmaceutical synthesis. Safety information indicates that users should exercise caution. The compound carries GHS hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate precautionary measures, such as P261 (Avoid breathing dust/fume/gas/mist/vapours/spray) and P305+P351+P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing), are advised to ensure safe handling in industrial environments.
For pharmaceutical companies and research institutions seeking a reliable manufacturer of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol, NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier supplier. We offer competitive price options for bulk quantities, ensuring cost-effectiveness without compromising on quality. To buy or purchase this essential intermediate, interested parties are invited to contact our sales team directly for detailed quotations and supply chain solutions. Our expertise in chemical synthesis and commitment to customer satisfaction position us as an ideal partner for your long-term supply needs. We understand the critical nature of timely delivery and consistent product specifications in the pharmaceutical supply chain and are dedicated to providing unparalleled service.
In conclusion, 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol (CAS: 121660-11-5) is a vital chemical intermediate with indispensable applications in the pharmaceutical industry, particularly in the synthesis of Pitavastatin. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading manufacturer and supplier of this high-quality compound, providing reliable solutions for global pharmaceutical production. Our dedication to excellence, competitive pricing, and robust supply capabilities make us the preferred choice for those looking to purchase this critical material.
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