2-Ethylbutyryl chloride (CAS 2736-40-5) stands as a versatile and indispensable chemical compound, recognized for its crucial role in various synthetic processes. As a key organic intermediate, it is widely utilized across the chemical and pharmaceutical industries, serving as a fundamental building block for the creation of more complex molecules. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of this high-quality compound, ensuring its purity and reliability for demanding applications.

This compound, with the molecular formula C6H11ClO and a molecular weight of 134.60 g/mol, is characterized by its appearance as a clear, colorless liquid. A high assay of ≥97.0% guarantees its efficacy in sensitive reactions. 2-Ethylbutyryl chloride exhibits a boiling point typically ranging from 137°C to 139°C and a density of approximately 0.982 g/mL at 25°C. Its flash point is around 33°C (91°F), indicating its flammability and necessitating careful handling. It is also known to react with water, emphasizing its moisture-sensitive nature.

The primary utility of 2-Ethylbutyryl chloride lies in its reactivity as an acylating agent, making it a valuable intermediate in a broad spectrum of organic syntheses. In the pharmaceutical industry, it is integral to the development and synthesis of novel drug compounds. For instance, it has been successfully employed in the synthesis of bicyclic thiophene derivatives, which are crucial components in drug discovery and the design of therapeutic agents. Its versatility extends to contributing to the creation of prostaglandin transport inhibitors and various other medicinal intermediates.

Beyond pharmaceuticals, 2-Ethylbutyryl chloride finds significant application in the wider chemical industry. It serves as a precursor for the production of a diverse array of specialty chemicals, including but not limited to fragrances, dyes, and additives. Its unique chemical structure allows for its incorporation into complex molecules through reactions like C-H arylation of methylene groups in cycloalkanes, the synthesis of 1,3-diketones and β-keto thioesters, and various palladium-catalyzed processes. The compound's role in creating organic luminescent materials and transition metal complexes further highlights its broad industrial relevance, contributing to advancements in materials science and optoelectronics.

Given its sensitive nature, proper storage and handling of 2-Ethylbutyryl chloride are paramount. It should be stored in a clean, dry, and cool environment, meticulously protected from direct sunlight, rain, and moisture. Due to its reactivity with water and oxidizing agents, as well as its flammability, it is essential to store it under an inert gas atmosphere and away from incompatible materials such as amines, alcohols, and active metals. Adherence to these storage guidelines is crucial for maintaining product integrity and ensuring laboratory safety.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a reliable manufacturer and supplier of high-purity 2-Ethylbutyryl chloride. We understand the critical importance of quality and consistency in chemical intermediates for research and industrial applications. For those looking to buy or purchase 2-Ethylbutyryl chloride, we offer competitive price options and ensure timely delivery. Our dedicated team is ready to assist with any inquiries regarding product specifications or bulk orders, reinforcing our position as a preferred partner in the chemical supply chain.