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2-Fluoro-4-iodoaniline: An Essential Intermediate for Chemical Synthesis

In the vast landscape of chemical compounds, certain molecules stand out for their indispensable role as intermediates, enabling the creation of a multitude of valuable end products. 2-Fluoro-4-iodoaniline (CAS 29632-74-4) is one such pivotal compound, a halogenated aromatic amine that serves as a cornerstone for complex organic synthesis across diverse industrial sectors. Its unique structural features and inherent reactivity make it a compound of considerable interest for researchers and manufacturers alike.

The chemical significance of 2-Fluoro-4-iodoaniline stems from its precise molecular architecture. The presence of both a fluorine atom and an iodine atom on the aniline ring offers distinct synthetic handles. Fluorine, known for its electronegativity, can influence the electronic properties and metabolic stability of derived molecules, a trait highly prized in pharmaceutical development. Iodine, being a larger and more polarizable halogen, acts as an excellent leaving group and is highly susceptible to participating in a wide array of transition-metal-catalyzed cross-coupling reactions. This dual functionality allows chemists to selectively introduce a variety of substituents, enabling the construction of intricate molecular frameworks. For professionals looking to buy such a versatile building block, its availability is crucial.

The physical and chemical properties of 2-Fluoro-4-iodoaniline further underscore its utility. Typically appearing as a light yellow to brown crystalline powder, it possesses a defined melting point range (55-57 °C), indicating a degree of purity. With a molecular formula of C6H5FIN and a molecular weight of 237.014, it fits the profile of many fine chemical intermediates. Its density and boiling point are also important parameters for chemists engaged in process development and scale-up. When considering procurement, understanding these specifications from a reliable manufacturer is essential for successful integration into synthesis pathways.

The applications of 2-Fluoro-4-iodoaniline are extensive and continue to expand. In the pharmaceutical industry, it is a key precursor for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents for oncology, antivirals, and other critical disease areas. Its strategic incorporation into drug molecules can enhance potency, selectivity, and pharmacokinetic profiles. Beyond pharmaceuticals, this intermediate finds application in the creation of agrochemicals, specialized dyes, and advanced materials, including components for organic electronics and sensors. For those looking to purchase this essential chemical, partnering with a reputable supplier like a leading manufacturer in China ensures both quality and competitive pricing.

In summary, 2-Fluoro-4-iodoaniline is more than just a chemical compound; it is an enabler of innovation. Its capacity to facilitate complex organic transformations makes it an invaluable asset in modern chemical synthesis. We are committed to providing this critical intermediate to support your research and industrial needs. Contact us to learn more about purchasing options and to secure your supply.

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

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