2-Iodo-4-(trifluoromethyl)benzoic acid, identified by its CAS number 54507-44-7, is a highly significant compound in the realm of organic chemistry and pharmaceutical synthesis. With a molecular formula of C8H4F3IO2 and a molecular weight of 316.02, this chemical serves as a crucial building block, facilitating the creation of complex molecules with specific functionalities. Its unique structure, featuring both an iodine atom and a trifluoromethyl group on a benzoic acid core, makes it exceptionally versatile for various chemical transformations and applications.

This compound typically presents as a white to off-white powder or solid, characterized by its high purity, often exceeding 97% or 98%. Understanding its physical and chemical properties is essential for safe and effective handling. 2-Iodo-4-(trifluoromethyl)benzoic acid is known to be slightly soluble, requiring specific conditions for dissolution in solvents. Furthermore, its light-sensitive nature necessitates storage in a dark place, sealed dry, and at room temperature, away from strong oxidizing agents to maintain its stability and reactivity over time. Proper storage protocols are paramount to preserving its quality for sensitive chemical processes.

The primary application of 2-Iodo-4-(trifluoromethyl)benzoic acid lies in its role as a vital intermediate for the synthesis of advanced pharmaceutical compounds. A notable example includes its use as a starting material for preparing 10-chloro-8-fluoro-10,11-dihydro-2-trifluoromethyldibenzothiepin, a complex structure often found in medicinal chemistry. The strategic incorporation of trifluoromethyl and iodine groups into target molecules can significantly enhance their biological activity, metabolic stability, and pharmacokinetic profiles. This makes 2-Iodo-4-(trifluoromethyl)benzoic acid indispensable for researchers and manufacturers developing next-generation therapeutics and other high-value chemicals.

Beyond its direct utility in pharmaceutical development, the compound’s distinct chemical profile also offers potential applications in other specialized fields. It can serve as a precursor in the synthesis of agrochemicals, functional materials, or fine chemicals where fluorinated and iodinated aromatic systems are required. Its reactivity allows for a diverse range of synthetic pathways, including Suzuki-Miyaura coupling, Heck reactions, and other cross-coupling reactions, making it a valuable asset for creating novel compounds with tailor-made properties for various industrial and research purposes.

For laboratories and industries worldwide, sourcing high-purity chemical intermediates like 2-Iodo-4-(trifluoromethyl)benzoic acid is critical for ensuring the success and reliability of their synthetic processes. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing premium quality chemical products, manufactured under stringent quality control standards. As a trusted manufacturer and supplier, our commitment extends to offering comprehensive technical support and competitive pricing to meet the diverse needs of our global clientele. Whether you are looking to buy or purchase this essential chemical for research or large-scale production, we ensure a seamless and reliable procurement experience.

In conclusion, 2-Iodo-4-(trifluoromethyl)benzoic acid (CAS: 54507-44-7) stands as a cornerstone in modern organic synthesis, particularly for the pharmaceutical sector. Its unique chemical properties and critical role in creating complex, high-value molecules underscore its importance. NINGBO INNO PHARMCHEM CO.,LTD. remains your reliable partner for acquiring this vital compound, ready to assist with your specific requirements and contribute to your research and manufacturing successes. We invite you to explore our offerings and experience our dedication to excellence in chemical supply.