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2-Naphthylboronic Acid (CAS 32316-92-0): A Key Organic Synthesis Intermediate

2-Naphthylboronic acid, identified by its CAS number 32316-92-0, stands as a pivotal chemical intermediate in the realm of modern organic synthesis. This boronic acid derivative, often appearing as an off-white or white solid, boasts a molecular formula of C10H9BO2 and a molecular weight of 171.99 g/mol. Its distinct chemical structure, featuring a naphthalene core appended with a boronic acid group, grants it exceptional reactivity and utility across various chemical transformations.


At NINGBO INNO PHARMCHEM CO.,LTD., we recognize the critical importance of high-purity raw materials in complex chemical processes. Our 2-Naphthylboronic acid is produced to meet stringent quality specifications, typically achieving a purity of ≥99.8% by HPLC. This ensures that our product provides reliable and consistent performance in demanding applications. The compound exhibits a melting point in the range of 269-275°C, indicative of its stable crystalline form, and is best stored in a cool, dry place, away from direct sunlight, to maintain its integrity.


The primary application of 2-Naphthylboronic acid lies in its role as a crucial building block for pharmaceutical intermediates and fine organic chemicals. It is extensively utilized in a variety of carbon-carbon and carbon-heteroatom bond-forming reactions, most notably the Suzuki-Miyaura cross-coupling. This palladium-catalyzed reaction facilitates the formation of biaryl systems and other complex organic architectures, which are fundamental to the synthesis of numerous active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. Beyond Suzuki-Miyaura coupling, it also finds utility in other organoboron reactions, including copper-mediated cross-couplings, direct C-H arylations, and thiol ester-boronic acid couplings, highlighting its versatility as a synthetic reagent.


The demand for high-quality 2-Naphthylboronic acid continues to grow as pharmaceutical research and development expand into more intricate molecular designs. Its ability to participate in highly selective and efficient reactions makes it indispensable for chemists striving to synthesize novel compounds with specific biological activities. As a reputable manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing superior-grade 2-Naphthylboronic acid to meet these evolving industry needs. We employ advanced manufacturing techniques and rigorous quality control measures to ensure that every batch of our product adheres to the highest standards of purity and consistency. This commitment ensures that our clients receive a reliable chemical that contributes to the success of their synthesis projects.


For those seeking a dependable source of 2-Naphthylboronic acid (CAS 32316-92-0), NINGBO INNO PHARMCHEM CO.,LTD. offers competitive pricing and efficient global shipping. Whether you need a small quantity for research and development or bulk amounts for industrial production, we are equipped to handle your requirements. To inquire about our product, request a quote, or discuss specific specifications, please contact us. We are confident in our ability to be your preferred manufacturer and supplier, facilitating your purchase process with ease and transparency. We invite you to explore how our high-quality 2-Naphthylboronic acid can benefit your next project and encourage you to buy or purchase from a trusted partner committed to excellence.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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