3,4,5-Trifluorophenol, identified by its CAS number 99627-05-1 and also known as PHENOL,3,4,5-TRIFLUORO, stands as a critical chemical intermediate in the realm of organic synthesis. With a molecular formula of C6H3F3O and a molecular weight of 148.08300, this compound is highly valued for its unique trifluorinated structure, which imparts distinct reactivity and properties crucial for developing advanced chemical products.
This compound presents as a white to light yellow crystalline powder, indicative of its high purity and solid state at room temperature. Its fundamental physical and chemical characteristics are well-defined: a density of 1.473, a melting point ranging from 52-55ºC, a boiling point of 177ºC, and a flash point also at 177ºC. The index of refraction is measured at 1.471. These precise specifications are vital for researchers and manufacturers, ensuring consistent performance and predictable reactions in complex synthetic pathways. The relatively low melting point allows for easier handling in its solid form, while its boiling and flash points provide important safety considerations for storage and processing.
Quality assurance is paramount for such a specialized intermediate. Our 3,4,5-Trifluorophenol consistently meets stringent purity standards, boasting an assay of ≥99.0%. Furthermore, its moisture content is meticulously controlled to be ≤0.2%, preventing unwanted side reactions and ensuring the integrity of downstream synthetic processes. This high level of purity is indispensable for applications where even trace impurities could compromise reaction efficiency or product quality, such as in pharmaceutical manufacturing.
The primary application of 3,4,5-Trifluorophenol lies in its extensive use as an organic synthesis intermediate. The strategic incorporation of fluorine atoms into organic molecules is a well-established strategy in modern drug discovery and agrochemical development. Fluorine can significantly alter a molecule's properties, including its lipophilicity, metabolic stability, pKa, and binding affinity to biological targets. As such, 3,4,5-Trifluorophenol serves as an invaluable precursor for synthesizing a diverse array of fluorinated compounds, ranging from active pharmaceutical ingredients (APIs) and advanced agrochemicals to specialized functional materials. Its versatile reactivity allows for its integration into various synthetic routes, making it a cornerstone for innovation in both academic research and industrial chemical production.
For optimal preservation of its quality and chemical integrity, 3,4,5-Trifluorophenol should be stored in a cool, well-ventilated place, away from direct sunlight and sources of ignition. It is typically supplied in robust 25 kg drums, though flexible packaging options are available to meet specific customer requirements, ensuring convenient handling and storage regardless of order size.
As a dedicated manufacturer and reliable supplier of high-quality chemical intermediates, we are committed to providing premium 3,4,5-Trifluorophenol. For those looking to buy or purchase this essential compound for their research or industrial needs, we offer competitive price options and efficient delivery. Our expertise ensures that you receive a product of consistent quality, essential for your most demanding applications.
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