NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the significance and broad-spectrum applications of 3,4-Dihydroxybenzaldehyde, also known by its common name Protocatechualdehyde. This organic compound, identified by the CAS number 139-85-5, is a cornerstone intermediate in the synthesis of numerous high-value products across the pharmaceutical, flavor, and fine chemical industries. With its unique molecular structure, C₇H₆O₃, this phenolic aldehyde represents a critical building block for innovation and development.

Chemical Profile and Quality Assurance

3,4-Dihydroxybenzaldehyde is a phenolic aldehyde that presents as a grayish-white to off-white solid powder. At NINGBO INNO PHARMCHEM CO.,LTD., we guarantee a product of the highest caliber. Our manufacturing process ensures a purity level of ≥99%, with stringent controls on moisture content (≤1.0% loss on drying) and residual monomers (≤0.5%). This commitment to quality ensures that our clients receive a consistent, reliable, and highly effective product batch after batch, suitable for the most sensitive applications. Every lot is accompanied by a detailed Certificate of Analysis, confirming its adherence to predefined specifications. This rigorous quality control is fundamental to our role as a trusted chemical supplier.

Expansive Pharmaceutical Applications

The therapeutic potential of Protocatechualdehyde is vast and well-documented, making it a prized ingredient in modern medicine. Its pharmacological activities are diverse, addressing several critical health areas:

Cardiovascular Health: It is widely recognized for its positive effects on the cardiovascular system. It functions by increasing coronary blood flow and dilating coronary arteries, which helps improve myocardial oxygen supply. This makes it an effective component in treatments for angina pectoris and coronary heart disease. Furthermore, it helps improve microcirculation and has shown antithrombotic effects by inhibiting platelet aggregation.

Anti-Inflammatory and Antioxidant Properties: The two hydroxyl groups on the benzene ring give 3,4-Dihydroxybenzaldehyde potent antioxidant capabilities. It is an excellent scavenger of free radicals, which helps to mitigate oxidative stress—a key factor in numerous chronic diseases. Its anti-inflammatory effects are also significant, making it a subject of interest for treating various inflammatory conditions.

Neuroprotective Effects: Emerging research has demonstrated its neuroprotective potential. Studies suggest that Protocatechualdehyde can protect dopaminergic neurons from neurotoxin-induced injury, indicating its potential utility in developing therapies for neurodegenerative diseases like Parkinson's disease.

Nephritis and Renal Protection: The compound has been identified as a key effective ingredient in the treatment of nephritis. Recent studies have explored its therapeutic effects in diabetic nephropathy, where it has been shown to reduce renal fibrosis and improve kidney function.

Oncological Research: Protocatechualdehyde has shown antiproliferative and pro-apoptotic properties against certain cancer cell lines, including human breast and colorectal cancer cells, by modulating key cellular pathways. This has opened new avenues for its investigation in cancer therapy.

A Crucial Intermediate in Chemical Synthesis

Beyond its direct therapeutic uses, 3,4-Dihydroxybenzaldehyde is an indispensable intermediate in organic synthesis.

Flavor and Fragrance Industry: It serves as a critical precursor in the synthesis of vanillin, one of the world's most popular flavoring agents. Its structure allows for methylation to produce methyl protocatechualdehyde, also known as vanillin. This application is vital for the food, beverage, and cosmetics industries. It is also used in the broader synthesis of various spices and aromas.

Fine Chemicals and Polymers: Its reactive nature makes it a valuable starting material for creating complex molecules, including various bioactive compounds, dyes, and specialty polymers. Researchers utilize it to synthesize novel 2-arylbenzothiazoles with anti-cancer potential and other heterocyclic systems with antimicrobial activities.

Partnering with NINGBO INNO PHARMCHEM CO.,LTD.

As a dedicated manufacturer of 3,4-Dihydroxybenzaldehyde, we understand the critical need for a stable and high-quality supply chain. We offer flexible packaging solutions, typically in 25kg cardboard drums, to meet diverse client requirements. Our production capacity and advanced logistics ensure that we can fulfill orders of varying sizes promptly and efficiently. For companies looking to buy or purchase this vital intermediate, we offer a competitive price without compromising on the quality or purity that is essential for your manufacturing processes. We invite you to purchase with confidence from a supplier that prioritizes excellence, consistency, and customer success. By choosing NINGBO INNO PHARMCHEM CO.,LTD., you are securing a partnership with a leading chemical manufacturer committed to empowering your innovation and production goals.