3,5-Dichloroaniline (CAS No: 626-43-7) stands as a pivotal chemical intermediate, widely recognized for its versatility and crucial role across various industries. Identified by its synonyms such as 1-amino-3,5-dichlorobenzene and m-Dichloroaniline, this compound is typically presented as a light yellow crystal or powder, indicating its high purity and crystalline structure. Its significance is primarily rooted in its extensive applications, particularly in the synthesis of high-performance agrochemicals, pharmaceuticals, and dyes, making it an indispensable building block in modern chemistry.

The compound exhibits distinct physical and chemical properties that contribute to its utility. With a molecular formula of C6H5Cl2N and a molecular weight of 162.017, 3,5-Dichloroaniline has a density of approximately 1.4±0.1 g/cm3. Its boiling point is recorded at 260.6±0.0 °C at 760 mmHg, while its melting point is around 49 °C, which aligns with observations from independent sources noting a range of 46-52 °C or 50.0-53.0 °C. The flash point is 118.3±21.8 °C, indicating its relatively stable nature under normal handling conditions. It has low water solubility at 0.6 g/L (26 ºC) and is best stored in a cool place, ideally between 0-6°C, with the container kept tightly closed in a dry and well-ventilated area to maintain its integrity and prevent degradation.

One of the primary applications of 3,5-Dichloroaniline is its use as a raw material in the agricultural sector. It serves as a key intermediate for the production of numerous fungicides and insecticides, including Dimethachlon (CAS: 24096-53-5), Vinclozolin (CAS: 50471-44-8), Iprodione (CAS: 36734-19-7), and Procymidone (CAS: 32809-16-8). Furthermore, it is instrumental in preparing compounds such as dimorphic sclerotin, sclerotinol, vinyl sclerotin, sclerotia, carbendazim, acetolide, and chlorfenapram. Beyond fungicides, this versatile compound is also utilized in the synthesis of various herbicides and plant growth regulators, playing a crucial role in enhancing crop protection and yield.

Beyond agriculture, 3,5-Dichloroaniline finds significant utility in the pharmaceutical industry, where it is employed in the synthesis of quinoline derivatives, compounds known for their efficacy in the treatment of malaria. This highlights its importance in the development of life-saving medications. In the dye industry, it is a key component in the manufacture of azo dyes and various pigments, contributing to a wide array of colored products. Its application extends to industrial hygiene as well, where it is used in the manufacture of pesticides and pest repellents, contributing to public health and safety.

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