For chemists and material scientists, the pursuit of novel molecules often hinges on the availability of versatile chemical building blocks. 3-Bromo-5-methylisoxazole, identified by its CAS number 25741-97-3, is one such compound that plays a significant role in advanced organic synthesis. This article aims to provide a comprehensive overview of its properties, applications, and crucial sourcing considerations.

Key Properties of 3-Bromo-5-methylisoxazole

3-Bromo-5-methylisoxazole is a heterocyclic organic compound with the molecular formula C4H4BrNO and a molecular weight of approximately 161.98 g/mol. Its physical state at standard conditions is typically a solid or liquid with a characteristic odor. Key documented properties include a boiling point of 202.1°C at 760 mmHg and a flash point of 76°C. Crucially for its applications, it is often available with a purity of 97% or higher. Its structure, featuring a reactive bromine atom on the isoxazole ring, dictates its utility in various chemical reactions.

Diverse Applications in Synthesis

The value of 3-bromo-5-methylisoxazole lies in its versatility as an intermediate. Its primary applications include:

• Pharmaceutical Synthesis: It serves as a critical building block for the creation of Active Pharmaceutical Ingredients (APIs) and drug candidates. Its isoxazole core can be found in various therapeutic agents.
• Agrochemical Development: The compound can be used in the synthesis of pesticides and herbicides, contributing to the protection of crops and enhancement of agricultural yields.
• Organic Chemistry Research: As a functionalized heterocyclic compound, it is a valuable reagent for exploring new synthetic pathways and developing novel organic molecules with specific properties.
• Material Science: Its structure may lend itself to applications in the development of specialized materials, though this is a less common, emerging area.

Strategic Sourcing for Optimal Results

When seeking to buy 3-bromo-5-methylisoxazole (CAS 25741-97-3), procurement professionals and researchers should focus on reliability and quality. It is recommended to source from manufacturers and suppliers with a proven track record. Key considerations include:

• Purity Verification: Always request a Certificate of Analysis (CoA) to confirm the purity level, typically 97%+, and ensure it meets your project's requirements.
• Supplier Reputation: Choose suppliers known for their consistency, quality control, and customer service. Companies with extensive experience in supplying chemical intermediates are preferable.
• Pricing and Quantity: Compare prices from multiple suppliers, especially for larger quantities. Bulk purchase options can often lead to significant cost savings.
• Lead Times and Logistics: Understand the estimated delivery times, particularly if sourcing internationally, to align with project schedules.

In summary, 3-bromo-5-methylisoxazole (CAS 25741-97-3) is a potent and versatile intermediate in organic synthesis. By carefully considering its properties, applications, and focusing on strategic sourcing from reputable manufacturers, researchers and businesses can effectively leverage this compound for their innovative projects.