3'-Chloropropiophenone (CAS 34841-35-5): A Versatile Chemical Intermediate

3'-Chloropropiophenone, identified by its CAS number 34841-35-5, is a high-purity chemical compound essential across numerous industrial sectors. Also known by its synonym, m-Chloropropiophenone, this compound plays a pivotal role as a key organic synthesis intermediate. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of this versatile chemical, ensuring the highest standards of quality and reliability for its global clientele.

Chemically, 3'-Chloropropiophenone possesses the molecular formula C9H9ClO and a molecular weight of 168.62 g/mol. It typically appears as a white to light yellow crystalline powder or solid, known for its refined quality and consistent physical properties. Key characteristics include a melting point ranging from 45 to 47°C and a boiling point of 124°C at 14 mmHg. Its density is approximately 1.1115, and it has a flash point exceeding 110°C, indicating its stability under appropriate handling conditions. This compound exhibits good solubility in organic solvents such as methanol, hot toluene, and alcohol, while being insoluble in water.

The applications of 3'-Chloropropiophenone are remarkably diverse, spanning from pharmaceutical development to specialized industrial uses. In the pharmaceutical industry, it serves as a crucial intermediate for synthesizing various therapeutic agents. Notably, it is an important precursor in the production of certain antidepressant drugs like bupropion and dapoxetine, highlighting its significance in modern medicine. Researchers also utilize it for the preparation of thizaine derivatives, which are explored for their potential antibacterial activities, further expanding its medicinal utility.

Beyond pharmaceuticals, 3'-Chloropropiophenone finds substantial application in the agrochemical sector. It is instrumental in the synthesis of components used in herbicides and pesticides, contributing to effective crop protection solutions and enhancing agricultural productivity. Its reactive nature makes it a valuable building block in the development of new chemical entities in this field. The fragrance industry also benefits from this compound, where it is incorporated into formulations to create unique scent profiles, enhancing the appeal of perfumes and cosmetic products.

Moreover, as a general research reagent, 3'-Chloropropiophenone is indispensable for synthetic chemists. It is widely employed in various organic reactions, including vinylation, alkylation, and dienylation of ketones, facilitating the development of novel synthetic pathways and complex molecules. In material science, this compound is utilized in the creation of polymers and other specialized materials, imparting specific properties that enhance product performance across diverse applications.

For safe handling and storage, 3'-Chloropropiophenone should be kept in a well-ventilated warehouse, protected from direct sunlight, fire, and moisture. It is advisable to store it in a dry, sealed container at room temperature, with some recommendations suggesting storage between 0-8°C for optimal preservation. While generally stable, precautions are necessary as it can be irritating to the skin, eyes, and respiratory system. Users should always adhere to standard safety protocols, including wearing appropriate personal protective equipment.

As a dedicated chemical manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering high-quality 3'-Chloropropiophenone. Our rigorous quality control processes ensure that every batch meets stringent purity specifications, typically at 98% or higher. We serve as a reliable supplier for businesses seeking to purchase this essential chemical intermediate. For those looking to buy 3'-Chloropropiophenone, we offer competitive prices and efficient global distribution. Whether you require a bulk purchase or smaller quantities, our team is ready to assist with your specific needs. Contact us today to learn more about our product offerings and how we can support your chemical sourcing requirements.