In the intricate landscape of pharmaceutical manufacturing, the selection of high-quality intermediates is a cornerstone of successful drug development and production. 4-Amino-1-butanol (CAS 13325-10-5) stands out as a critical building block, valued for its unique chemical structure and versatile reactivity. For procurement specialists and R&D scientists in the pharmaceutical sector, understanding the role and sourcing of this compound is vital. This article highlights the significance of 4-Amino-1-butanol as a pharmaceutical intermediate and guides on how to effectively purchase it from reliable manufacturers.

The Chemical Profile of 4-Amino-1-butanol

4-Amino-1-butanol, also known by synonyms such as 4-aminobutanol and 4-hydroxybutylamine, is an alkanolamine. Its molecular formula is C4H11NO, and it typically appears as a white powder with a purity of 98% or higher. This bifunctional molecule, possessing both an amine and a hydroxyl group, allows for a wide range of chemical transformations, making it an indispensable intermediate in synthesizing complex organic molecules. Its structure is closely related to GABA (gamma-aminobutyric acid), suggesting its potential in neurochemical research and development.

Significance as a Pharmaceutical Intermediate

The pharmaceutical industry relies heavily on intermediates that can be efficiently converted into active pharmaceutical ingredients (APIs). 4-Amino-1-butanol fits this role perfectly due to:

• Versatile Reactivity: The presence of both primary amine and primary alcohol functional groups allows for diverse derivatization, enabling the synthesis of a broad spectrum of drug candidates.
• Building Block for APIs: It is frequently employed in the synthesis pathways of various therapeutic agents, including those targeting neurological disorders, and other complex organic drugs.
• Chiral Synthesis: In certain contexts, it can be utilized in asymmetric synthesis to create enantiomerically pure compounds, which is crucial for drug efficacy and safety.
• Precursor for GABA Analogues: Its structural similarity to GABA makes it a valuable starting material for research into GABAergic systems and related therapeutics.

Procuring 4-Amino-1-butanol: What to Look For

When seeking to buy 4-Amino-1-butanol for pharmaceutical applications, several factors are paramount:

• Purity: Pharmaceutical-grade purity (typically 98%+) is essential. Always request a Certificate of Analysis (CoA) from the manufacturer.
• Regulatory Compliance: Ensure the supplier adheres to quality standards relevant to pharmaceutical intermediates.
• Reliable Supply: For drug manufacturing, a consistent and dependable supply chain is critical. Work with a 4-Amino-1-butanol supplier that can guarantee production capacity and timely delivery.
• Competitive Pricing: Securing the best possible price for intermediates is key to cost-effective drug production. Getting a quote from established Chinese manufacturers is a common practice for bulk purchases.

For pharmaceutical companies looking to source this vital intermediate, partnering with a reputable 4-Amino-1-butanol manufacturer is the first step towards successful drug development. Whether you need small quantities for R&D or large volumes for production, engaging with a trusted supplier for CAS 13325-10-5 ensures quality and reliability.