In the realm of fine chemicals, understanding the specific properties and applications of each compound is crucial for successful research and manufacturing. 4-Aminoacetanilide (CAS 122-80-5) stands out as a key intermediate with a defined set of characteristics that make it valuable across multiple industrial sectors. This article delves into the chemical properties of 4-Aminoacetanilide and its significant roles, particularly in the dye and pharmaceutical industries, offering insights for procurement and R&D professionals looking to purchase this compound.

Chemical Profile of 4-Aminoacetanilide

4-Aminoacetanilide, chemically known as N-(4-Aminophenyl)acetamide or N-Acetyl-p-phenylenediamine, is characterized by its molecular formula C8H10N2O and a molecular weight of 150.18 g/mol. Its physical appearance is typically described as white or reddish crystals. The compound exhibits a melting point in the range of 164–167 °C, indicating its solid state under standard conditions.

Key chemical properties include:

• Purity: It is commercially available with a guaranteed purity of 98% minimum, with many suppliers offering higher grades, such as 99% or more. This high purity is vital for ensuring predictable reaction kinetics and the quality of end products.
• Solubility: 4-Aminoacetanilide is slightly soluble in water, with solubility reported as 0.1-1 g/100 mL at 25 °C. It shows better solubility in organic solvents.
• Reactivity: The presence of both an amino group and an acetamido group on the benzene ring makes it a versatile reactant. The amino group can undergo diazotization, a key step in azo dye synthesis, while the entire molecule can serve as a building block in organic synthesis.

Industrial Significance and Applications

The industrial utility of 4-Aminoacetanilide is primarily concentrated in two major areas:

• Dye Industry: As an intermediate, it plays a pivotal role in the production of various azo dyes. These include specific dyes used for textiles, such as disperse yellow G, direct acid-resistant vermilion 4BS, and acid-resistant fuchsin 6B. The ability to form stable diazonium salts makes it invaluable for creating a spectrum of colors. Companies looking to buy dye intermediates will find this a staple product.
• Pharmaceutical Industry: 4-Aminoacetanilide also serves as a crucial intermediate in the synthesis of pharmaceuticals. Its structure can be incorporated into more complex drug molecules, contributing to their efficacy. Researchers and manufacturers in the pharmaceutical sector often source this compound for developing new therapeutic agents.

Procurement Considerations for Buyers

When you intend to buy 4-Aminoacetanilide, it is essential to consider factors like purity, supplier reputation, and price. Manufacturers and suppliers, especially those in global hubs like China, offer competitive pricing and reliable supply chains. Understanding the typical assay of the product you are purchasing (e.g., 98% min vs. 99% min) can inform your decision-making process for large-scale production or sensitive pharmaceutical applications.

In conclusion, 4-Aminoacetanilide is a chemical compound of significant industrial importance due to its well-defined properties and its critical role as an intermediate in the dye and pharmaceutical industries. For professionals looking to purchase this essential chemical, focusing on quality and reliable supply from reputable sources is key to successful integration into their manufacturing processes.