In the intricate world of chemical synthesis and research, the availability of specialized intermediates is fundamental to innovation. 4-Bromo-2,3,5,6-tetrafluoropyridine (CAS 3511-90-8) stands out as a particularly versatile and valuable compound for scientists and researchers. Its distinct chemical structure makes it an indispensable tool for exploring new molecular pathways and developing advanced materials.

Understanding the Chemical Identity and Properties

As a fluorinated heterocyclic compound, 4-Bromo-2,3,5,6-tetrafluoropyridine offers unique reactivity. The presence of a bromine atom provides a convenient handle for various substitution and coupling reactions, while the electron-withdrawing nature of the four fluorine atoms significantly influences the electron density of the pyridine ring. This makes it an attractive substrate for nucleophilic aromatic substitution and organometallic chemistry. Typically supplied with a minimum purity of 97%, its physical characteristics include being a clear, colorless liquid. Key parameters such as a boiling point of 134-135°C and a density of 1.208 g/cm³ (at 25°C) are crucial for laboratory handling and process design. For procurement specialists, verifying these specifications is a first step in ensuring the suitability of the material for their intended application.

Applications in Research and Development

The primary utility of 4-Bromo-2,3,5,6-tetrafluoropyridine lies in its role as a research chemical and an intermediate in organic synthesis. It is a vital precursor for generating highly reactive organometallic species, specifically tetrafluoro-pyridylcadmium and tetrafluoro-pyridylzinc reagents. These intermediates are essential in modern synthetic chemistry, enabling the formation of carbon-carbon bonds with high precision, often employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Researchers utilize this compound to introduce fluorinated pyridine moieties into larger molecular frameworks, which can impart desirable properties such as increased metabolic stability, lipophilicity, or altered electronic characteristics.

Sourcing Strategies: China Manufacturers and Price Considerations

For many global research and development teams, identifying reliable and cost-effective sources for such specialized chemicals is a strategic imperative. China has become a leading global supplier of fine chemicals and intermediates, offering high-quality products like 4-Bromo-2,3,5,6-tetrafluoropyridine at competitive prices. When looking to buy this compound, it is advisable to seek out manufacturers that emphasize stringent quality control and provide comprehensive product documentation. The price of 4-Bromo-2,3,5,6-tetrafluoropyridine can vary based on purity, quantity, and the supplier's origin. Engaging with direct manufacturers or their authorized distributors can often yield the best value, especially for bulk purchases or ongoing supply needs. The availability of free samples can also be a valuable tool for quality assessment before committing to a larger order.

Conclusion: A Fundamental Building Block for Innovation

4-Bromo-2,3,5,6-tetrafluoropyridine is more than just a chemical compound; it is an enabler of scientific discovery. Its unique fluorinated structure and reactivity make it a cornerstone intermediate for chemists developing next-generation compounds. For research institutions and chemical companies worldwide, understanding its properties and sourcing it efficiently from reputable suppliers, particularly those in China offering competitive pricing and reliable quality, is key to advancing innovation in chemical science.