NINGBO INNO PHARMCHEM CO.,LTD. highlights the importance of 4-Bromo-2-fluoropyridine (CAS: 128071-98-7), a critical chemical intermediate that underpins many advancements in pharmaceutical research and sophisticated organic synthesis.
4-Bromo-2-fluoropyridine, also known as 2-Fluoro-4-bromopyridine, is defined by its molecular formula C5H3BrFN and a molecular weight of 175.99. It typically appears as a colorless to light yellow liquid, with properties such as a density of approximately 1.7 g/cm³ and a flash point of around 72°C. These physical and chemical characteristics are fundamental to its role as a reactive intermediate. The detailed CAS 128071-98-7 chemical properties offer insights into its utility.
As a primary pharmaceutical intermediate, 4-Bromo-2-fluoropyridine is essential for the synthesis of Active Pharmaceutical Ingredients (APIs). Its structure allows it to participate effectively in reactions like the Suzuki-Miyaura cross-coupling, a vital process for creating complex molecular structures needed in drug development. It is notably used in the synthesis of isoquinolinone derivatives, which are investigated for various therapeutic applications.
The compound's versatility extends to its use as a fundamental organic building block, enabling chemists to explore novel molecular designs and synthetic pathways. The presence of reactive halogen atoms provides strategic points for functionalization and modification, crucial for fine-tuning the properties of newly synthesized compounds.
The global market for fine chemicals and pharmaceutical intermediates sees significant contributions from China. Sourcing from fine chemical manufacturers in China is often advantageous for companies seeking quality and competitive pricing for materials like 4-Bromo-2-fluoropyridine. Adherence to best practices for the handling and storage of halogenated pyridines is crucial for maintaining product efficacy and safety.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the chemical and pharmaceutical industries by providing essential intermediates like 4-Bromo-2-fluoropyridine, thereby contributing to scientific progress and the development of new medicines.
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