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At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying the essential chemical components that drive innovation. This article focuses on 4-Bromo-2-fluoropyridine (CAS: 128071-98-7), a versatile and crucial intermediate in the fields of pharmaceutical development and advanced organic synthesis.
4-Bromo-2-fluoropyridine is a heterocyclic organic compound characterized by its pyridine core substituted with bromine and fluorine atoms. This structural configuration grants it significant reactivity, making it a highly valuable building block. Its molecular formula is C5H3BrFN, and it has a molecular weight of approximately 175.99. The compound is typically presented as a colorless to light yellow liquid, possessing a density of about 1.7 g/cm³ and a flash point of around 72°C. These physical and chemical properties are vital for its effective use in various synthetic processes, forming the basis of its CAS 128071-98-7 chemical properties.
The primary application of 4-Bromo-2-fluoropyridine is its function as a pharmaceutical intermediate. It is extensively used in the synthesis of Active Pharmaceutical Ingredients (APIs), where its unique structure facilitates the creation of complex molecular architectures required for modern drugs. The compound is particularly noted for its participation in cross-coupling reactions, such as the Suzuki-Miyaura coupling, a cornerstone of modern organic synthesis that enables the efficient formation of carbon-carbon bonds. This makes it indispensable for the synthesis of isoquinolinone derivatives and other advanced pharmaceutical compounds.
Chemists leverage the reactivity of 4-Bromo-2-fluoropyridine to introduce specific functionalities and build intricate molecular scaffolds. Its role as a versatile organic building block extends its utility beyond immediate pharmaceutical applications, supporting broader research into novel chemical entities and synthetic methodologies. The ability to precisely control reactions involving this intermediate is a significant advantage for research and development.
The global supply of specialty chemicals often relies on efficient manufacturing capabilities, with China playing a significant role. Companies looking for reliable sources of 4-Bromo-2-fluoropyridine often turn to fine chemical manufacturers in China. These suppliers are known for their ability to produce high-purity materials at competitive price points, ensuring that research institutions and manufacturing plants have consistent access to this vital intermediate. Understanding the nuances of handling and storage of halogenated pyridines is also key to successful procurement and utilization.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the scientific community by providing high-quality chemical intermediates. Our offering of 4-Bromo-2-fluoropyridine is part of our mission to empower advancements in pharmaceutical research, drug discovery, and the broader chemical synthesis landscape.
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