4-chloro-2-fluoro-aniline, also known by its synonyms such as 2-fluoro-4-chloro-aniline, 4-chloro-2-fluorobenzenamine, and 4-chloro-2-fluoro-phenylamine, stands as a critical chemical intermediate in a diverse range of industries. With the molecular formula C6H5ClFN and a molecular weight of 145.56200, this compound exhibits distinctive physical and chemical properties that make it highly valuable for complex synthesis.

Typically appearing as a colorless to dark amber liquid with a characteristic aniline smell, 4-chloro-2-fluoro-aniline has a density of 1.311 g/mL at 25 °C. Its boiling point ranges from 104-107 °C (at 28 mmHg), and it possesses a flash point of 210 °F. The refractive index is measured at n20/D 1.56, and it shows slight solubility in water. For optimal preservation of its integrity and reactivity, it is recommended to store this compound at room temperature.

As a chemical intermediate, 4-chloro-2-fluoro-aniline plays a pivotal role in multi-step chemical synthesis. Chemical intermediates are substances generated during the conversion of initial reactants into desired products. They are often characterized by their transient nature and high reactivity, serving as essential building blocks that connect different stages of a reaction pathway. While these substances are formed and consumed within the overall reaction mechanism, they are fundamental for achieving specific synthetic routes and constructing complex molecular structures.

The applications of 4-chloro-2-fluoro-aniline span across several high-value sectors, including medicine, pesticides, and liquid crystal materials. In the pharmaceutical industry, intermediates are indispensable raw materials that bridge the gap between active therapeutic molecules and final drug products. The introduction of fluorine atoms into pharmaceutical intermediates, as seen in 4-chloro-2-fluoro-aniline, is particularly significant. Fluorine-containing drugs are highly sought after due to their advantageous characteristics, such as lower dosage requirements, reduced toxicity, enhanced efficacy, and improved metabolic stability. This makes 4-chloro-2-fluoro-aniline a key component in the development of advanced pharmaceutical compounds.

Beyond medicine, this compound is vital in the production of pesticides, contributing to the synthesis of effective agrochemicals that protect crops and enhance agricultural productivity. Its properties enable the creation of specific chemical structures required for modern pesticide formulations. Furthermore, in the realm of advanced materials, 4-chloro-2-fluoro-aniline is employed as an intermediate in the manufacturing of liquid crystal materials. These materials are fundamental to display technologies, influencing the performance and clarity of screens found in a wide array of electronic devices.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 4-chloro-2-fluoro-aniline, adhering to stringent factory standards. Our analysis confirms a purity level of 98.51%, exceeding the typical requirement of ≥98.0%, ensuring reliability for sensitive applications. Our dedication as a leading manufacturer and supplier means we focus on consistent product quality and efficient supply chain management to meet global demands. For those looking to purchase this essential chemical intermediate, whether for research and development or large-scale production, we offer competitive prices and robust technical support. To inquire about the price or to buy 4-chloro-2-fluoro-aniline, please contact our sales team. We ensure a seamless procurement process for all our partners.