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4-Chloro-2-methylpyridine: A Key Intermediate for Organic Synthesis

4-Chloro-2-methylpyridine (CAS No. 3678-63-5) stands as a pivotal chemical compound, widely recognized for its indispensable role as an organic synthesis intermediate. This colorless liquid, also known by its synonyms such as 4-Chloro-2-picoline or 2-methyl-4-chloropyridine, possesses a unique chemical structure that makes it highly valuable in the creation of a diverse array of advanced organic molecules. Its precise composition, denoted by the molecular formula C6H6ClN and a molecular weight of 127.572 g/mol, underscores its specific chemical properties that are leveraged across various industrial sectors.


The physical and chemical characteristics of 4-Chloro-2-methylpyridine are crucial for its effective application in complex synthetic pathways. It exhibits a density of approximately 1.2±0.1 g/cm3, indicating its relative specific gravity. A key property for its handling and application is its boiling point, which measures around 163.5±20.0 °C at 760 mmHg, facilitating controlled reactions under specific temperature conditions. Furthermore, its flash point of 65.6±7.4 °C is an important safety parameter for storage and processing. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this compound consistently meets stringent quality standards, with an assay typically registering at ≥99.0% purity, guaranteeing optimal performance in sensitive chemical reactions.


As a versatile building block, 4-Chloro-2-methylpyridine serves as a critical precursor in numerous organic synthesis applications. Its reactive chlorine atom and pyridine ring make it an excellent starting material for introducing pyridine moieties into complex target molecules. This capability is particularly significant in the development and manufacturing of pharmaceuticals, agrochemicals, and specialty chemicals. In the pharmaceutical industry, it can contribute to the synthesis of active pharmaceutical ingredients (APIs) and their intermediates, enabling the creation of new therapeutic compounds. For agrochemicals, it plays a role in producing herbicides, insecticides, and fungicides, essential for modern agriculture. Beyond these, its utility extends to the development of dyes, pigments, and advanced material sciences, where its unique structural features are exploited to achieve desired properties in the final products.


Proper handling and storage are paramount to maintain the integrity and purity of 4-Chloro-2-methylpyridine. It is recommended to store this chemical in a cool, well-ventilated area, away from direct sunlight and incompatible substances. NINGBO INNO PHARMCHEM CO.,LTD. provides this product in standard 200 kg drums, with flexible packaging options available to cater to specific customer requirements, ensuring safe and efficient delivery worldwide. Our commitment to quality extends from manufacturing to logistics, guaranteeing product stability and efficacy upon arrival.


For businesses seeking a reliable manufacturer and supplier of high-quality 4-Chloro-2-methylpyridine, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing superior chemical products with unwavering consistency. We understand the critical nature of purity and reliability in chemical synthesis, and our advanced production processes reflect this commitment. To inquire about the current price or to buy/purchase 4-Chloro-2-methylpyridine, we encourage prospective clients to reach out to our sales team. We offer competitive pricing and flexible terms to meet the diverse needs of global chemical industries, ensuring a seamless procurement experience for this essential organic synthesis intermediate.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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