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The ongoing battle against HIV/AIDS has seen significant advancements in treatment, with Rilpivirine emerging as a crucial medication. The efficacy of Rilpivirine is intrinsically linked to the quality of its precursors, and foremost among these is the pharmaceutical intermediate 4-[(4-Chloro-2-pyrimidinyl)amino]-benzonitrile, identified by its CAS number 244768-32-9. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the profound impact this compound has on global health initiatives.
4-[(4-Chloro-2-pyrimidinyl)amino]-benzonitrile serves as a fundamental building block in the multi-step synthesis of Rilpivirine. As a non-nucleoside reverse transcriptase inhibitor (NNRTI), Rilpivirine plays a vital role in suppressing viral replication in individuals living with HIV. The chemical precision required to synthesize Rilpivirine means that the quality of each intermediate, including 4-chloro-2-pyrimidinylamino-benzonitrile, is critical. A high-purity compound, such as the one with an assay of ≥99.0%, ensures that the subsequent reactions proceed efficiently and that the final drug product meets stringent pharmaceutical standards.
The consistent availability of this Rilpivirine intermediate is essential for maintaining a stable supply of the medication worldwide. Pharmaceutical companies rely on consistent access to materials like 4-[(4-Chloro-2-pyrimidinyl)amino]-benzonitrile from reputable suppliers to meet patient demand. The compound's physical characteristics, such as its powder form and specified impurity limits, are carefully managed by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. to facilitate its integration into complex manufacturing processes.
Understanding the various 4-chloro-2-pyrimidinylamino-benzonitrile uses extends beyond its direct role in Rilpivirine synthesis; it signifies the importance of specialized chemical manufacturing in supporting public health. By providing high-quality intermediates, NINGBO INNO PHARMCHEM CO.,LTD. contributes directly to making advanced HIV treatments accessible to those who need them. We are dedicated to ensuring the reliable supply of this vital compound, supporting the ongoing efforts to combat HIV/AIDS globally.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
