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4-Chloroanisole: A Versatile Intermediate for Organic Synthesis

4-Chloroanisole, also known by its chemical name 1-Chloro-4-methoxybenzene, and synonyms such as p-Anisyl chloride and P-Chloroanisole, is a vital compound in the realm of organic chemistry. Identified by its CAS number 623-12-1, this chemical plays a crucial role as an intermediate in various synthesis processes. At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying high-quality 4-Chloroanisole, ensuring its efficacy and reliability for diverse industrial and research applications.


Our 4-Chloroanisole typically presents as a colorless transparent liquid, signifying its high purity. It possesses a molecular formula of C7H7ClO and a molecular weight of 142.58. Key physical and chemical properties include a density of approximately 1.1 g/cm3 and a boiling point around 184.4±13.0 °C at 760 mmHg, though it can range up to 198-202 °C. The melting point is consistently reported at −18 °C. With a flash point of 78.3±0.0 °C, appropriate handling and storage are essential. Its vapor pressure is approximately 1.0±0.3 mmHg at 25°C, and the index of refraction is measured at 1.515. Furthermore, 4-Chloroanisole is immiscible with water and exhibits good stability, though it is combustible and incompatible with strong oxidizing agents, requiring careful handling and storage protocols.


The applications of 4-Chloroanisole are remarkably diverse, extending far beyond its primary use as an intermediate in organic synthesis. It is a valuable industrial solvent, contributing to various manufacturing processes. Research has highlighted its fungicidal activity, suggesting potential for applications in agricultural or material protection. This electron-rich chloroarene is also utilized in the production of polyurethanes, showcasing its versatility in polymer chemistry. Its reactive nature allows it to participate in complex reactions, such as Ullmann-type homocoupling, a powerful method for carbon-carbon bond formation. Studies also reveal its reactions with substances like Cu(II)-smectite and its involvement in nucleophilic photosubstitution reactions, including photocyanation and photohydrolysis. Moreover, 4-Chloroanisole has been observed to facilitate reactions such as Suzuki coupling and cationic polymerization reactions, often requiring the formation of a solid catalyst in the presence of specific ions.


At NINGBO INNO PHARMCHEM CO.,LTD., we ensure that our 4-Chloroanisole meets stringent quality standards, with an assay specification of ≥99.0%. This commitment to purity guarantees optimal performance in sensitive chemical processes. For safety and product integrity, 4-Chloroanisole should be stored in a cool, ventilated place, away from strong oxidizing agents and ignition sources. We understand the importance of secure and efficient packaging, offering our product in 200 kg drums, with additional options available to meet specific customer requirements.


As a leading manufacturer and supplier of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is poised to meet your demands for 4-Chloroanisole. We strive to offer competitive price options while maintaining superior product quality and reliable delivery. To buy or purchase this essential organic synthesis intermediate, we encourage you to reach out to our dedicated sales team. We are committed to providing excellent service and a seamless procurement process for all your industrial and research needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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